Robert M. Schainfeld, DO; Jeffrey M. Isner, MD
Schainfeld R., Isner J.; Critical Limb Ischemia: Nothing To Give at the Office?. Ann Intern Med. 1999;130:442-444. doi: 10.7326/0003-4819-130-5-199903020-00017
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Published: Ann Intern Med. 1999;130(5):442-444.
The prognosis for patients with chronic critical leg ischemia—that is, pain at rest or established lesions that jeopardize the integrity of the lower limbs—is often poor (1). Psychological testing of such patients has typically disclosed quality-of-life indices similar to those of patients with cancer in critical or even terminal phases (2). It has been estimated that 150 000 patients require lower-limb amputation for critical leg ischemia in the United States annually (3). The prognosis after amputation is even worse (4): In most series, the perioperative mortality is 5% to 10% for below-the-knee amputation and 15% to 20% for above-the-knee amputation. Even when these patients survive, nearly 40% will die within 2 years of their first major amputation. A second amputation is required in 30% of cases, and full mobility is achieved in only 50% of patients who have below-the-knee amputation and 25% of those who have above-the-knee amputation.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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