Osamu Kabutomori, BSc; Yoshinori Iwatani, MD; Miwako Kabutomori, BSc
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Kabutomori O, Iwatani Y, Kabutomori M. Effects of Hypertriglyceridemia on Platelet Counts in Automated Hematologic Analysis. Ann Intern Med. 1999;130:452. doi: 10.7326/0003-4819-130-5-199903020-00011
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Published: Ann Intern Med. 1999;130(5):452.
TO THE EDITOR:
Levels of chylomicron are increased in the sera of patients with hypertriglyceridemia. Chylomicrons, which contain triglyceride in high concentrations, are usually 0.5 to 1.0 µm in diameter (1). Sometimes, however, they reach a diameter of 1.5 to 3.5 µm, which is equal to the size of a platelet in peripheral blood (2). Therefore, we examined the effect of hypertriglyceridemia on platelet counts measured with two types of automated hematologic analyzers: the NE-8000 (Sysmex, Kobe, Japan), which uses the electrical impedance method, and the THMS-H2 (Bayer, West Haven, Connecticut), which uses the optical method (3).
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