Jaime Soto, MD; Jonathan Berman, MD, PhD
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
Soto J., Berman J.; Primaquine Prophylaxis against Malaria. Ann Intern Med. 1999;130:536-537. doi: 10.7326/0003-4819-130-6-199903160-00020
Download citation file:
Published: Ann Intern Med. 1999;130(6):536-537.
The comments of Heppner and colleagues and Dr. Barry are useful and contribute to a dialogue on the important subject of malaria prophylaxis.
We appreciate Heppner and colleagues' emphasis on points that we also emphasized: the risk of giving primaquine to G6PD-deficient persons and the higher efficacy of the drug for P. falciparum than for P. vivax. We also appreciate the comments on the question of mefloquine in pregnancy. When we stated that “the risk of mefloquine prophylaxis … has not been clinically evaluated,” we might have added the word “thoroughly” before “clinically evaluated.” The risk has been and is being examined, and reasonable persons can disagree on the drug's safety in pregnancy (1, 2). We chose not to take sides and simply implied that final evaluation remains.
to gain full access to the content and tools.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only