Ulrich R. Hengge, MD; Manfred Goos, MD; Rüdiger Arndt, MD
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Hengge U., Goos M., Arndt R.; Topical Treatment of Warts and Mollusca with Imiquimod. Ann Intern Med. 2000;132:95. doi: 10.7326/0003-4819-132-1-200001040-00024
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Published: Ann Intern Med. 2000;132(1):95.
TO THE EDITOR:
Despite numerous therapeutic options, the treatment of common warts and mollusca contagiosa remains unsatisfactory for both patients and physicians. Epidemiologic studies estimate the prevalence of nongenital cutaneous warts at 0.78% to 22%, with a peak occurring in young adolescents (1). The incidence of common warts and mollusca contagiosa is especially high in persons with atopic dermatitis, diabetes, and immunodeficiency (2).
Current treatments rely on the ablation of warts or the interruption of cell division (3). Imiquimod, a novel topical immune response modifier, has been successfully used for the treatment of external anogenital warts (4). We evaluated the safety, tolerability, and efficacy of self-applied 5% imiquimod cream for the treatment of common cutaneous warts and mollusca contagiosa in heavily pretreated patients (mean treatments, 2.7; average duration of warts or mollusca contagiosa, 29.2 and 9.8 months, respectively).
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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