Shinichi Okamura; Horiuchi Katsuhiko; Teturou Satoh
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Okamura S, Katsuhiko H, Satoh T. Regression of Rectal Mucosa-Associated Lymphoid Tissue Lymphoma Unrelated to Helicobacter pylori. Ann Intern Med. 2000;132:247. doi: 10.7326/0003-4819-132-3-200002010-00023
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Published: Ann Intern Med. 2000;132(3):247.
TO THE EDITOR:
It is rare for low-grade lymphoma of mucosa-associated lymphoid tissue (MALT) to affect the rectum, and eradication of Helicobacter pylori may cause regression of rectal MALT lymphoma (1). We describe a 54-year-old man with rectal MALT lymphoma that was unrelated to H. pylori and that regressed spontaneously.
The patient was referred for evaluation of small nodular elevations in the rectum. His bone marrow and peripheral blood were normal, but he had uncontrolled diabetes mellitus. Initial biopsy specimens from the rectum showed diffuse centrocyte-like cells in the mucosal and submucosal layer. These cells were confirmed as a monoclonal B-lymphocyte population by immunohistochemistry. Upper endoscopy revealed chronic gastritis, but H. pylori infection was not detected by any feasible examination, including 13C-urea breath test, urease test, culture, and histologic and serologic investigations. Computed tomography and ultrasonography showed no lymphadenopathy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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