Todd B. Seto, MD, MPH; Deborah A. Taira, ScD; Ronna Berezin, MPH; Manish S. Chauhan, MD; Donald E. Cutlip, MD; Kalon K.L. Ho, MD, MSc; Richard E. Kuntz, MD, MSc; David J. Cohen, MD, MSc
Acknowledgments: The authors thank Roger Davis, ScD, and John Spertus, MD, for thoughtful review of an earlier draft of this manuscript.
Grant Support: In part by a Clinician-Scientist Award from the American Heart Association (Dr. Cohen) and an unrestricted grant from Guidant, Inc. (Santa Clara, California).
Requests for Single Reprints: David J. Cohen, MD, MSc, Cardiovascular Division, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215.
Current Author Addresses: Dr. Seto: Queen's Medical Center, 1301 Punchbowl Street, Honolulu, HI 96813.
Dr. Taira: Hawaii Medical Service Association, Care Management, 818 Keeaumoku Street, Honolulu, HI 96814.
Ms. Berezin: Cardiovascular Data Analysis Center, 900 Commonwealth Avenue, 2nd Floor, Boston, MA 02215.
Drs. Chauhan, Ho, Kuntz, and Cohen: Cardiovascular Division, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215.
Dr. Cutlip: University of Rochester Medical Center, Rochester, NY 14620.
Author Contributions: Conception and design: T.B. Seto, D.A. Taira, R.E. Kuntz, D.J. Cohen.
Analysis and interpretation of the data: T.B. Seto, D.A. Taira, R. Berezin, D.E. Cutlip, K.K.L. Ho, D.J. Cohen.
Drafting of the article: T.B. Seto, D.A. Taira, D.J. Cohen.
Critical revision of the article for important intellectual content: T.B. Seto, D.A. Taira, M.S. Chauhan, D.E. Cutlip, K.K.L. Ho, R.E. Kuntz, D.J. Cohen.
Final approval of the article: T.B. Seto, D.A. Taira, R. Berezin, M.S. Chauhan, D.E. Cutlip, K.K.L. Ho, R.E. Kuntz, D.J. Cohen.
Statistical expertise: R.E. Kuntz, D.J. Cohen.
Obtaining of funding: D.J. Cohen.
Administrative, technical, or logistic support: R. Berezin, M.S. Chauhan, D.E. Cutlip.
Collection and assembly of data: R. Berezin, M.S. Chauhan, D.E. Cutlip, K.K.L. Ho, R.E. Kuntz.
Percutaneous coronary intervention (PCI) is frequently performed in elderly patients, but little is known about its impact on overall health and quality of life.
To examine changes in health-related quality of life among elderly patients after PCI.
75 U.S. hospitals.
Participants in two clinical trials of PCI.
Health-related quality of life was assessed by using the Medical Outcomes Study Short Form (SF-36) survey and the Seattle Angina Questionnaire at baseline, 6 months, and 1 year.
Serial data on health-related quality of life were available for 295 elderly (≥ 70 years) and 1150 nonelderly (<70 years) patients. At 6 months, physical health had improved in 51% of elderly patients and mental health had improved in 29%. Cardiovascular-specific health status had improved in 58% to 75% of elderly patients. Improvement did not significantly differ between elderly and nonelderly patients at 6 months or 1 year.
Elderly patients selected for participation in a trial of PCI had substantial improvements in health-related quality of life after PCI that were similar to those in younger patients.
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Seto TB, Taira DA, Berezin R, Chauhan MS, Cutlip DE, Ho KK, et al. Percutaneous Coronary Revascularization in Elderly Patients: Impact on Functional Status and Quality of Life. Ann Intern Med. 2000;132:955-958. doi: 10.7326/0003-4819-132-12-200006200-00005
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Published: Ann Intern Med. 2000;132(12):955-958.
Cardiology, Coronary Heart Disease, Geriatric Medicine, Percutaneous Coronary Intervention.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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