Immaculada Grau, MD; Josefina Liñares, MD; Roman Pallares, MD
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Grau I., Liñares J., Pallares R.; Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California. Ann Intern Med. 2000;132:1009. doi: 10.7326/0003-4819-132-12-200006200-00032
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Published: Ann Intern Med. 2000;132(12):1009.
TO THE EDITOR:
Nuorti and colleagues (1) reported on the epidemiology of invasive pneumococcal disease in HIV-infected patients in San Francisco. They found that this population had a high incidence of invasive pneumococcal infections. Even more important, they observed a significant reduction in pneumococcal disease among patients with AIDS, probably as a result of the wider use of highly active antiretroviral therapy.
In our institution, we noted a significant reduction in the number of HIV-infected patients among all patients with bacteremic pneumococcal infections: 38 of 198 (19.2%) in 1994–1996 and 25 of 224 (11.2%) in 1997–1999 (P = 0.02). As occurred in our study (2), Nuorti and colleagues found that the mortality rate did not differ between patients with and those without HIV infection; this could be due to the relatively younger age of HIV-infected patients.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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