Norton J. Greenberger, MD
Greenberger NJ. Update in Gastroenterology. Ann Intern Med. 2000;133:542-548. doi: 10.7326/0003-4819-133-7-200010030-00014
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Published: Ann Intern Med. 2000;133(7):542-548.
This Update summarizes important developments published during the past year concerning clinical problems frequently encountered by practicing internists. New points are cited from several of the ongoing debates in the gastroenterology literature. The Update is divided into sections on the esophagus, acid peptic disease and Helicobacter pylori, gastrointestinal effects of cyclooxygenase-2 inhibitors, intestinal disease, cancer, and hepatobiliary disease. In addition, each section includes several “fast facts” to communicate briefly several newsworthy items.
The incidence of adenocarcinoma of the esophagus and gastric cardia has increased sharply in the last decade. Because the reasons for this increase are unclear, researchers in Sweden conducted a nationwide case–control study to determine the epidemiologic association between gastroesophageal reflux and these tumors. One hundred eighty-nine patients with adenocarcinoma of the esophagus, 262 patients with adenocarcinoma of the cardia, 167 patients with squamous-cell carcinoma of the esophagus, and 820 controls were grouped according to symptoms of gastroesophageal reflux.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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