Murray Grossman, MD
Grossman M.; Hormone Therapy and the Brain: A Clinical Perspective on the Role of Estrogen. Ann Intern Med. 2000;133:660. doi: 10.7326/0003-4819-133-8-200010170-00029
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Published: Ann Intern Med. 2000;133(8):660.
Henderson VW. 120 pages. New York: Parthenon; 2000. $58.00. ISBN 1850700788. Order phone 800-735-4744.
Field of medicine: General internal medicine, geriatric medicine, obstetrics and gynecology, and neurology.
Format: Hardcover book.
Audience: Clinicians; residents; and students of internal medicine, geriatrics, obstetrics and gynecology, and neurology.
Purpose: To teach physicians and trainees about the beneficial effects of estrogen supplementation for neurologic conditions.
Content: An introductory chapter covers the basic physiology and pharmacology of estrogen. Two subsequent chapters summarize the studies indicating the efficacy of estrogen in reducing postmenopausal depression and memory difficulties in otherwise healthy women, two important clinical targets of estrogen supplementation. Estrogen has been shown to be effective in several specific neurologic conditions as well, and the remainder of the book reviews studies documenting the role of estrogen treatment in these conditions. For example, patients with dementing conditions, such as Alzheimer disease and vascular dementia, benefit from estrogen therapy because it stabilizes their memory decline. In addition, estrogen may improve epilepsy, movement disorders, and migraine headache. Estrogen also appears to modify the frequency of stroke in patients with cerebrovascular disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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