Hashem B. El-Serag, MD, MPH
El-Serag HB. Segment Length and Risk for Neoplastic Progression in Patients with Barrett Esophagus. Ann Intern Med. 2000;133:747-748. doi: 10.7326/0003-4819-133-9-200011070-00025
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Published: Ann Intern Med. 2000;133(9):747-748.
TO THE EDITOR:
In Rudolph and colleagues' study (1), the cancer incidence in patients with Barrett esophagus segments longer than 10 cm was substantially higher than the incidence in patients whose segment was less than 3 cm long (7 per 100 person-years vs. 2.5 per 100 person-years). The authors concluded that the risk for esophageal adenocarcinoma in patients with short-segment Barrett esophagus was not substantially lower than that in patients with longer segments. However, the study did not have enough power to adequately detect statistically significant differences in the risk for cancer between these two groups of patients while controlling for potential confounders.
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