Brian J. McMahon, MD; Peter Holck, PhD; Lisa Bulkow, MS; Mary Snowball, RN
McMahon BJ, Holck P, Bulkow L, Snowball M. Serologic and Clinical Outcomes of 1536 Alaska Natives Chronically Infected with Hepatitis B Virus. Ann Intern Med. 2001;135:759-768. doi: 10.7326/0003-4819-135-9-200111060-00006
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Published: Ann Intern Med. 2001;135(9):759-768.
Data shown for carriers of hepatitis B surface antigen who were persistently HBeAg positive throughout follow-up (solid line); those who seroconverted from HBeAg positivity to anti-HBe positivity (dashed line); those who seroconverted from HBeAg to anti-HBe, then had reactivation of HBeAg (dotted line); and those who were initially anti-HBe negative, then had reactivation and tested HBeAg positive (smaller dashed line). Those who were persistently HBeAg negative and anti-HBe positive (group D in Table 1) are not shown.
Line patterns represent carriers who seroconverted from HBeAg to anti-HBe; those who seroconverted from HBeAg to anti-HBe, then had reactivation of HBeAg; those who were persistently HBeAg negative and anti-HBe positive; and those who were initially anti-HBe positive, then had reactivation of HBeAg.
The center solid line represents participants 20 years of age or older; the center dotted line represent participants younger than 20 years of age. The lines on either side of the center lines are 95% CIs, which are largely nonoverlapping.
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Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology, Infectious Disease, Liver Cancer.
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