J. Carlos Ayus, MD; Allen I. Arieff, MD
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Ayus J., Arieff A.; Sex Differences in Long-Term Mortality after Myocardial Infarction. Ann Intern Med. 2001;135:1089. doi: 10.7326/0003-4819-135-12-200112180-00015
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Published: Ann Intern Med. 2001;135(12):1089.
TO THE EDITOR:
We read with great interest the article by Vaccarino and colleagues concerning the increased mortality rate associated with myocardial infarction in younger women (1). The mortality rate in women was significantly higher than that in men (20.9% vs. 13.6%), and among patients younger than 50 years of age, the risk for death was three times higher in women than in men. After analysis for numerous demographic and clinical characteristics, as well as cardiac therapy during hospitalization, the authors found no obvious answer to explain the increased mortality rate in young women. They suggested several possible mechanisms, including genetic, hormonal, or inflammatory factors (1).
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