Viola Vaccarino, MD, PhD; Robert J. Goldberg, PhD
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
Vaccarino V., Goldberg R.; Sex Differences in Long-Term Mortality after Myocardial Infarction. Ann Intern Med. 2001;135:1090-1091. doi: 10.7326/0003-4819-135-12-200112180-00018
Download citation file:
Published: Ann Intern Med. 2001;135(12):1090-1091.
Drs. Ayus and Arieff, Dr. Franco-Bronson and coworkers, and Dr. Friedman present interesting hypotheses regarding possible underlying mechanisms for the higher mortality risk in younger women compared with men. Drs. Ayus and Arieff hypothesize that the effects of sex hormones on the regulation of the myocardial circulation, possibly mediated by vasopressin, may lead to increased coronary vasoconstriction. Although, as they note, these effects have been described in the cerebral circulation in the setting of hyponatremic encephalopathy, it is unknown whether similar effects apply to the coronary circulation. There is some evidence, however, that women are more subject to coronary vasospasm than men (1); therefore, this hypothesis is worth exploring in future studies.
to gain full access to the content and tools.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only