Cécile Vigneau, MD; David Petrover, MD; Jean-Daniel Sraer, MD, PhD
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
Vigneau C, Petrover D, Sraer J. Late Occurrence of Chronic Renal Failure in Familial Mediterranean Fever after 20 Years of Colchicine Treatment. Ann Intern Med. 2001;135:1096. doi: 10.7326/0003-4819-135-12-200112180-00030
Download citation file:
Published: Ann Intern Med. 2001;135(12):1096.
TO THE EDITOR:
Since 1972, colchicine has been used to treat familial Mediterranean fever. Colchicine has good efficacy for reducing frequency of attacks and renal amyloidosis in both native and transplanted kidneys, even at the nephrotic stage (1-4). We report two cases of chronic renal failure due to amyloidosis despite very long treatment with colchicine in patients with familial Mediterranean fever.
In 1982, a 46-year-old Sepharad man was admitted to the hospital because of attacks of familial Mediterranean fever and the nephrotic syndrome. Amyloidosis was proved by kidney biopsy. With colchicine treatment, proteinuria disappeared. The nephrotic syndrome reappeared in April 2000 with renal failure despite good adherence to treatment. Renal biopsy showed a massive infiltration of AA amyloidosis.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only