Muhammed S. Karim, MD; Muhammed K. Athar, MD; Michel W. Ghobrial, MD
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Karim MS, Athar MK, Ghobrial MW. Superior Sagittal Sinus Thrombosis and HIV. Ann Intern Med. 2002;137:375. doi: 10.7326/0003-4819-137-5_Part_1-200209030-00035
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Published: Ann Intern Med. 2002;137(5_Part_1):375.
TO THE EDITOR:
Although myriad neurologic complications have been reported in patients with HIV infection, thromboembolic phenomena have been limited to scattered reports. Most of these reports have been anecdotal and have implicated lupus anticoagulant, anticardiolipin antibody, and protein S deficiency (1-3). To our knowledge, cerebral venous sinuses thrombosis, a rare disease described as early as 1825, has not been described as an initial presentation of HIV.
A 34-year-old man presented with right-sided weakness. The patient had no family history of premature cardiac or cerebrovascular events. He had no history of recent falls or head trauma. He did not have fever, visual symptoms, or neck pain. Other than an oral temperature of 37.7 °C, his vital signs were normal. Neurologic examination revealed right-sided hemiparesis and an upper motor neuron weakness of his right seventh cranial nerve. The rest of his physical examination was unremarkable. The following laboratory findings were either normal or negative: complete blood count, serum chemistry, calcium level, liver function tests, thyroid function test results, coagulation profile, blood alcohol level, and urine toxicologic screen.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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