Michael P. LaValley, PhD; David T. Felson, MD, MPH
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
LaValley MP, Felson DT. Truth Survival. Ann Intern Med. 2002;137:932. doi: 10.7326/0003-4819-137-11-200212030-00016
Download citation file:
Published: Ann Intern Med. 2002;137(11):932.
TO THE EDITOR:
While we applaud Poynard and colleagues for addressing the issue of truth survival in clinical research (1), we feel that the data they collected are biased and misleading. Poynard and colleagues sampled studies on cirrhosis and hepatitis from 1945 to 1999. Experts were asked if the main conclusion from each study was true, false, or obsolete as of the year 2000. False or obsolete studies were considered to have the event of interest, and studies considered still true were censored at the year 2000. With this approach, the time to event should have been the time from publication of a research study until its results became either false or obsolete. For example, studies published in 1950 and made obsolete in 1965 would have 15 years of survival. However, Poynard and colleagues determined that truth survival was the time from publication to the year 2000. Therefore, a study published in 1950 and made obsolete in 1965 would be credited with 50 years of survival rather than the correct 15 years. This systematically overestimates the truth survival of false or obsolete research.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only