Allison L. Naleway, PhD; Edward A. Belongia, MD; Robert T. Greenlee, PhD, MPH; Burney A. Kieke, MS; Robert T. Chen, MD, MA; David K. Shay, MD, MPH
Naleway AL, Belongia EA, Greenlee RT, Kieke BA, Chen RT, Shay DK. Eczematous Skin Disease and Recall of Past Diagnoses: Implications for Smallpox Vaccination. Ann Intern Med. 2003;139:1-7. doi: 10.7326/0003-4819-139-1-200307010-00006
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Published: Ann Intern Med. 2003;139(1):1-7.
People with a history of atopic dermatitis or eczema in themselves or their close contacts should not receive preexposure smallpox vaccination because of the risk for eczema vaccinatum.
This population-based study suggests that about 40% of people would not correctly report that they or a close contact has these skin conditions even though medical records confirm that they do.
Relying on patient self-report about dermatologic contraindications to smallpox vaccination would miss a substantial proportion of people with true contraindications.
Recall was considered accurate if a participant gave a positive response to questions on history of any of the following: atopic dermatitis diagnosis, eczema diagnosis, or recurrent rash.
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Bioterrorism Infectious Agents, Infectious Disease, Prevention/Screening, Vaccines/Immunization.
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