Geraldo Castelar Pinheiro, MD; Morton A. Scheinberg, MD, PhD; Miriam Aparecida da Silva, BS; Suely Maciel, BS
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Pinheiro G., Scheinberg M., Aparecida da Silva M., Maciel S.; Anti–Cyclic Citrullinated Peptide Antibodies in Advanced Rheumatoid Arthritis. Ann Intern Med. 2003;139:234-235. doi: 10.7326/0003-4819-139-3-200308050-00023
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Published: Ann Intern Med. 2003;139(3):234-235.
TO THE EDITOR:
Background: Rheumatoid arthritis is a chronic systemic autoimmune disease of unknown cause. There is growing evidence that therapeutic intervention early in the disease course leads to better control and less joint damage. With more sophisticated types of therapy becoming available, it is now even more important to definitively diagnose rheumatoid arthritis at an early stage so that treatment can be administered sooner and major damage of joint tissue can be prevented (1). A disease-specific autoantibody that could be used as a serologic marker of the disease would be very useful.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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