Jennifer Fisher Wilson
Wilson JF. Angiogenesis Therapy Moves beyond Cancer. Ann Intern Med. 2004;141:165-168. doi: 10.7326/0003-4819-141-2-200407200-00027
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Published: Ann Intern Med. 2004;141(2):165-168.
Doctors in different subspecialties, have, over the years, learned that people with Down syndrome have unsurpassed protection against certain diseases. Cancer is almost unheard of among people with this syndrome, according to oncologists. Noncongenital heart problems rarely afflict this population, according to cardiologists. And diabetic retinopathy never develops among people with both Down syndrome and diabetes, according to endocrinologists. But, until recently, most doctors only knew that Down syndrome provided protection; they did not know why.
They knew that people with Down syndrome had 3 copies of chromosome 21 (trisomy 21), but no one made the link between the extra chromosome and the protective effects of Down syndrome.
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