John T. Watson, MD, MSc; Peter E. Pertel, MD, MPH; Roderick C. Jones, MPH; Alicia M. Siston, MPH; William S. Paul, MD, MPH; Constance C. Austin, DVM, PhD, MPH; Susan I. Gerber, MD
Potential Financial Conflicts of Interest: None disclosed.
Corresponding Author: John T. Watson, MD, Chicago Department of Public Health, 2160 West Ogden, Chicago, IL 60612; e-mail, email@example.com.
Current Author Addresses: Drs. Watson, Paul, and Gerber, Mr. Jones, and Ms. Siston: Chicago Department of Public Health, 2160 West Ogden, Chicago, IL 60612.
Dr. Pertel: Bayer Pharmaceuticals, 400 Morgan Lane, West Haven, CT 06516.
Dr. Austin: Illinois Department of Public Health, 525 West Jefferson Street, Springfield, IL 62761.
Author Contributions: Conception and design: J.T. Watson, P.E. Pertel, R.C. Jones, W.S. Paul, S.I. Gerber.
Analysis and interpretation of the data: J.T. Watson, P.E. Pertel, R.C. Jones, A.M. Siston, S.I. Gerber.
Drafting of the article: J.T. Watson, P.E. Pertel, R.C. Jones.
Critical revision of the article for important intellectual content: J.T. Watson, P.E. Pertel, R.C. Jones, A.M. Siston, W.S. Paul, C.C. Austin, S.I. Gerber.
Final approval of the article: J.T. Watson, P.E. Pertel, R.C. Jones, A.M. Siston, W.S. Paul, C.C. Austin, S.I. Gerber.
Provision of study materials or patients: C.C. Austin.
Statistical expertise: R.C. Jones, A.M. Siston.
Collection and assembly of data: J.T. Watson, P.E. Pertel.
Watson JT, Pertel PE, Jones RC, Siston AM, Paul WS, Austin CC, et al. Clinical Characteristics and Functional Outcomes of West Nile Fever. Ann Intern Med. 2004;141:360-365. doi: 10.7326/0003-4819-141-5-200409070-00010
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Published: Ann Intern Med. 2004;141(5):360-365.
The frequency of infection with West Nile virus is increasing rapidly in the United States. While the most fatal and closely studied manifestations of the disease are meningitis and encephalitis, little is known about the symptoms and clinical outcomes of West Nile fever.
The authors interviewed 98 people with nonparalytic West Nile fever following recovery. Muscle weakness, fatigue, headache, difficulty concentrating, and fever were common manifestations. Approximately one third of patients required hospitalization. Median time to full recovery was 60 days.
Even in the absence of neurologic manifestations, West Nile virus infection is a potentially severe and debilitating illness.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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