Delphine Hu, MD, MPH; Edward W. Hook, MD; Sue J. Goldie, MD, MPH
Acknowledgments: The authors thank Karen Kuntz for guidance on probabilistic sensitivity analysis and Steven Sweet for technical advice and help with manuscript preparation.
Grant Support: By Agency for Healthcare Research and Policy Fellowship Award (Dr. Hu).
Potential Financial Conflicts of Interest:Consultancies: E.W. Hook (Abbott Laboratories, Gen-Probe); Honoraria: E.W. Hook (Abbott Laboratories, Gen-Probe); Other: E.W. Hook (Abbott Laboratories; Roche Molecular Systems, Inc.; Gen-Probe; Becton, Dickinson, and Co).
Requests for Single Reprints: Sue J. Goldie, MD, MPH, Department of Health Policy and Management, Harvard School of Public Health, 718 Huntington Avenue, 2nd Floor, Boston, MA 02115-5924.
Current Author Addresses: Drs. Hu and Goldie: Department of Health Policy and Management, Harvard School of Public Health, 718 Huntington Avenue, 2nd Floor, Boston, MA 02115-5924.
Dr. Hook: Department of Medicine, University of Alabama at Birmingham, 703 19th Street South ZRB 242, Birmingham, AL 35294-0007.
Author Contributions: Conception and design: D. Hu, S.J. Goldie.
Analysis and interpretation of the data: D. Hu, E.W. Hook, S.J. Goldie.
Drafting of the article: D. Hu, S.J. Goldie.
Critical revision of the article for important intellectual content: D. Hu, E.W. Hook, S.J. Goldie.
Final approval of the article: D. Hu, E.W. Hook, S.J. Goldie.
Statistical expertise: S.J. Goldie.
Administrative, technical, or logistic support: S.J. Goldie.
Hu D, Hook EW, Goldie SJ. Screening for Chlamydia trachomatis in Women 15 to 29 Years of Age: A Cost-Effectiveness Analysis. Ann Intern Med. 2004;141:501-513. doi: 10.7326/0003-4819-141-7-200410050-00006
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Published: Ann Intern Med. 2004;141(7):501-513.
Annual screening for Chlamydia trachomatis in sexually active women younger than 25 years of age is cost-effective, but the economic implications of more recent recommendations to expand screening to older women and to test more frequently in women with previous infection are unknown.
The cost-effectiveness of annual screening in women 15 to 29 years of age followed by semiannual screening in those with previous infection is well within the range of other accepted health care interventions. In some scenarios, such as high-prevalence populations, screening was cost-saving.
Recently proposed screening recommendations for Chlamydia trachomatis are cost-effective.
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Infectious Disease, Healthcare Delivery and Policy, Sexually Transmitted Infections, Prevention/Screening.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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