Lauris C. Kaldjian, MD
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
Kaldjian LC. Survival versus Prognosis in Alzheimer Disease. Ann Intern Med. 2004;141:575. doi: 10.7326/0003-4819-141-7-200410050-00019
Download citation file:
Published: Ann Intern Med. 2004;141(7):575.
TO THE EDITOR:
Larson and colleagues (1) concluded that Alzheimer disease significantly reduces survival. They suggested that a clinical evaluation can detect “features associated with prognosis for survival,” and an accompanying editorial (2) also emphasized prognostic implications. Larson and colleagues' reference to prognosis is juxtaposed with their acknowledgment that they have no reliable data on causes of death in their study sample. Prognosis refers to the “foretelling of the probable course of a disease” (3). In the context of Alzheimer disease, the contrast between “survival” and “prognosis” may be significant. Progressive neurodegeneration requires ongoing decisions about life-sustaining therapies (4, 5). These decisions respond to the trajectory of the underlying disease, but they also reflect the complex values and goals of patients and their surrogates. Decisions and disease are related but independent realities.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only