Marc C. Froissart, MD, PhD; Jerome Rossert, MD, PhD; Pascal Houillier, MD, PhD
Potential Financial Conflicts of Interest: None disclosed.
Froissart MC, Rossert J, Houillier P. The New Mayo Clinic Equation for Estimating Glomerular Filtration Rate. Ann Intern Med. 2005;142:679. doi: 10.7326/0003-4819-142-8-200504190-00028
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Published: Ann Intern Med. 2005;142(8):679.
TO THE EDITOR:
Rule and colleagues (1) analyzed a series of 580 potential kidney donors referred to the Mayo Clinic and found that the abbreviated Modification of Diet in Renal Disease (MDRD) equation significantly underestimated glomerular filtration rate (GFR) in healthy persons (1). This led the authors to develop new equations (refit MDRD equation for healthy persons, refit MDRD equation with healthy indicator, and a quadratic equation) that performed better than the abbreviated MDRD formula in healthy persons. However, as Stevens and Levey pointed out in their accompanying editorial (2), proper evaluation of these equations requires testing in an independent population.
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