Nassim P. Assefi, MD; Karen J. Sherman, PhD; Clemma Jacobsen, MS; Jack Goldberg, PhD; Wayne R. Smith, PhD; Dedra Buchwald, MD
Acknowledgments: The authors thank the research staff at the University of Washington (Roxanne Geller, Leigh Kochan, and Jovine Umali) and at the Clinical Monitoring Unit at the Group Health Cooperative Center for Health Studies (Rene Talenti, John Ewing, and Christel Kratohvil), the acupuncturists, and the study participants.
Grant Support: By grant RO1AT00003 from the National Center for Complementary and Alternative Medicine.
Potential Financial Conflicts of Interest: Grants received: N.P. Assefi, J. Goldberg, W.R. Smith, D. Buchwald (National Center for Complementary and Alternative Medicine).
Corresponding Author: Dedra Buchwald, MD, Box 359780, 1730 Minor Avenue, Suite 1760, Seattle, WA 98101.
Current Author Addresses: Dr. Assefi: Management Sciences for Health, House 24, Darulaman Road, Ayub Khan Mina, Kabul, Afghanistan.
Drs. Buchwald, Goldberg, and Smith and Ms. Jacobsen: Box 359780, 17360 Minor Avenue, Suite 1700, Seattle, WA 98101.
Dr. Sherman: 1730 Minor Avenue, Suite 1600, Seattle, WA 98101.
Author Contributions: Conception and design: K.J. Sherman, D. Buchwald.
Analysis and interpretation of the data: N.P. Assefi, K.J. Sherman, C. Jacobsen, J. Goldberg, W.R. Smith, D. Buchwald.
Drafting of the article: N.P. Assefi, K.J. Sherman, C. Jacobsen.
Critical revision of the article for important intellectual content: N.P. Assefi, K.J. Sherman, C. Jacobsen, J. Goldberg, W.R. Smith, D. Buchwald.
Final approval of the article: N.P. Assefi, K.J. Sherman, C. Jacobsen, J. Goldberg, W.R. Smith, D. Buchwald.
Provision of study materials or patients: D. Buchwald.
Statistical expertise: C. Jacobsen, J. Goldberg, W.R. Smith.
Administrative, technical, or logistic support: N.P. Assefi, K.J. Sherman, W.R. Smith.
Collection and assembly of data: N.P. Assefi, K.J. Sherman, C. Jacobsen, W.R. Smith.
Assefi NP, Sherman KJ, Jacobsen C, Goldberg J, Smith WR, Buchwald D. A Randomized Clinical Trial of Acupuncture Compared with Sham Acupuncture in Fibromyalgia. Ann Intern Med. 2005;143:10-19. doi: 10.7326/0003-4819-143-1-200507050-00005
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Published: Ann Intern Med. 2005;143(1):10-19.
A substantial number of patients use acupuncture to treat the symptoms of fibromyalgia, but previous randomized trials of this intervention are inconclusive, in part because of control groups that did not permit adequate blinding of the patients.
This study randomly assigned 100 patients with fibromyalgia to 12 weeks of either true acupuncture treatment or one of 3 types of sham acupuncture. No differences in pain were identified between acupuncture and sham acupuncture.
The study had too few patients to detect small differences between the groups. Patients could use other fibromyalgia therapies, so this study evaluates acupuncture as adjunctive treatment.
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Rheumatology, Chronic Fatigue Syndrome/Fibromyalgia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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