Margaret L. Brandeau, PhD
Potential Financial Conflicts of Interest: None disclosed.
Requests for Single Reprints: Margaret L. Brandeau, PhD, Department of Management Science and Engineering, Terman Building, Stanford University, Stanford, CA 94305-4026; e-mail, firstname.lastname@example.org.
Brandeau ML. Modeling Complex Medical Decision Problems with the Archimedes Model. Ann Intern Med. 2005;143:303-304. doi: 10.7326/0003-4819-143-4-200508160-00012
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Published: Ann Intern Med. 2005;143(4):303-304.
How often should women 40 to 50 years of age undergo mammography? Could an HIV vaccine with only limited effectiveness be a cost-effective means of slowing the spread of HIV infection? What is the best work-up for a patient who has a suspected pulmonary embolism?
In the ideal world, one would like free, fast, and ethical clinical trials that would provide the evidence needed to answer such questions. In the real world, these clinical trials may be too time-consuming, too expensive, unethical, or even impossible to perform. How, then, can we obtain useful answers about appropriate methods for disease prevention and treatment? We need a structured framework that uses the best evidence, imperfect as it may be, and captures relevant complexities and interactions. Decision models fulfill these requirements.
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Cardiology, Endocrine and Metabolism, Infectious Disease, Diabetes, HIV.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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