Ramachandran S. Vasan, MD; Michael J. Pencina, PhD; Mark Cobain, PhD; Matthew S. Freiberg, MD; Ralph B. D'Agostino, PhD
Grant Support: In part by the National Institutes of Health and National Heart, Lung, and Blood Institute contract N01-HC-38038. Dr. Vasan was partly supported by National Institutes of Health and National Heart, Lung, and Blood Institute grant 2K24 HL 04334.
Potential Financial Conflicts of Interest: Employment: M. Cobain (Unilever).
Requests for Single Reprints: Ramachandran S. Vasan, MD, The Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, MA 01702-5803; e-mail, email@example.com.
Current Author Addresses: Dr. Vasan: The Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, MA 01702-5803.
Drs. Pencina and D'Agostino: Boston University, 111 Cummington Street, Boston, MA 02135.
Dr. Cobain: Unilever Research, Colworth House, Sharnbrook, Bedforshire MK44 1LQ, United Kingdom.
Dr. Freiberg: University of Pittsburgh and Epidemiology Center for Research on Health Care, 230 McKee Place, Suite 600, Pittsburgh, PA 15213.
Author Contributions: Conception and design: R.S. Vasan, M.J. Pencina, R.B. D'Agostino.
Analysis and interpretation of the data: R.S. Vasan, M.J. Pencina, M. Cobain, M.S. Freiberg, R.B. D'Agostino.
Drafting of the article: R.S. Vasan, M.J. Pencina, M.S. Freiberg.
Critical revision of the article for important intellectual content: R.S. Vasan, M.J. Pencina, M. Cobain, M.S. Freiberg, R.B. D'Agostino.
Final approval of the article: R.S. Vasan, M.J. Pencina, M. Cobain, M.S. Freiberg, R.B. D'Agostino.
Statistical expertise: M.J. Pencina, R.B. D'Agostino.
Obtaining of funding: R.S. Vasan, R.B. D'Agostino.
Collection and assembly of data: R.B. D'Agostino.
Vasan R., Pencina M., Cobain M., Freiberg M., D'Agostino R.; Estimated Risks for Developing Obesity in the Framingham Heart Study. Ann Intern Med. 2005;143:473-480. doi: 10.7326/0003-4819-143-7-200510040-00005
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Published: Ann Intern Med. 2005;143(7):473-480.
What are the risks for becoming overweight or obese after age 30 years?
This study tracked 4117 normal-weight white adults 30 to 59 years of age who participated in the Framingham Offspring Study during 1971 to 2001. Within 4 years, 14% to 19% of the women and 26% to 30% of the men became overweight and 5% to 9% of both groups became obese. Within 30 years, more than half of both groups became overweight and about one third of the women and one quarter of the men became obese.
Long-term risks for white U.S. adults developing obesity are very high.
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