Gregory A. Poland, MD
Potential Financial Conflicts of Interest: Grants received: Merck.
Requests for Single Reprints: Gregory A. Poland, MD, Mayo Vaccine Research Group, Mayo Clinic and Foundation, 611C Guggenheim Building, 200 First Street SW, Rochester, MN 55905.
Poland GA. The Growing Paradigm of Preventing Disease: Vaccines To Prevent Herpes Zoster and Pertussis in Adults. Ann Intern Med. 2005;143:539-541. doi: 10.7326/0003-4819-143-7-200510040-00013
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Published: Ann Intern Med. 2005;143(7):539-541.
Two recent studies have shown the safety and efficacy of vaccines designed to prevent infectious diseases occurring among adults—herpes zoster (shingles) and pertussis (1, 2). The availability of these vaccines expands the growing paradigm of active disease prevention in adults. An acellular pertussis vaccine is now approved by the U.S. Food and Drug Administration (FDA) and available for use in adults (Adacel, Sanofi Pasteur, Swiftwater, Pennsylvania); the zoster vaccine (Zostavax, Merck Research Laboratories, New York, New York) is pending licensure application.
It is estimated that approximately 1 million cases of herpes zoster occur in the United States each year. As internists, it is important to note that we will often be confronted with this disease because of the ever-increasing age of the population and longer survival of people with disease- or drug-induced immunosuppression.
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Infectious Disease, Vaccines/Immunization, Prevention/Screening.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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