John M. Byrne, DO
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Byrne JM. Evidence-Based Medicine and the Search for a Science of Clinical Care. Ann Intern Med. 2005;143:772. doi: 10.7326/0003-4819-143-10-200511150-00035
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Published: Ann Intern Med. 2005;143(10):772.
Daly J. 290 pages. Berkeley, CA: Univ California Pr; 2005. $65.00. ISBN 0520243161. Order at http://www.ucpress.edu.
Field of medicine: Evidence-based medicine and clinical epidemiology.
Format: Hardcover book.
Audience: Teachers, students, and evidence-based medicine practitioners.
Purpose: To provide a comprehensive history of the origins and development of evidence-based medicine and its permeation into clinical practice.
Content: The author details the emergence of evidence-based medicine as a scientific method for clinical decision making and traces the intellectual contributions of its leaders. She articulates the rationale for evidence-based medicine but also challenges its tenets by enumerating the history and work of its many detractors. The author discusses the ascendance of the randomized, controlled trial and the elevation of meta-analyses as the preeminent science of clinical care, along with the limitations of applying clinical trial data to complex patient care decisions. The book challenges evidence-based medicine's focus, direction, and reach in clinical care, patient participation, research, medical economics, and public policy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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