Robert L. Frye, MD*
*Adapted for publication in Annals of Internal Medicine by Jennifer Fisher Wilson and Michael Berkwits, MD, MSCE.
Requests for Single Reprints: Robert L. Frye, MD, Mayo Clinic, Siebens Building, Room 640, 200 First Street SW, Rochester, MN 55905; e-mail, email@example.com.
Potential Financial Conflicts of Interest: Consultancies: Cleveland Clinic, Sanofi-Synthelabo Research. Honoraria: Cleveland Clinic, Sanofi-Synthelabo Research; all honoraria were paid to the Mayo Clinic and not the author. Grants received: Abbott Laboratories, Bayer Diagnostics, Becton Dickinson, Centocor, Bristol-Myers Squibb Medical Imaging (formerly DuPont), Eli Lilly and Company, Fujisawa Healthcare, GlaxoSmithKline, Merck & Co., Pfizer; all were received in support of BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes), a National Heart, Lung, and Blood Institute and National Institute of Diabetes and Digestive and Kidney Diseases Clinical Trial.
Frye RL. Update in Cardiology. Ann Intern Med. 2007;147:180-186. doi: 10.7326/0003-4819-147-3-200708070-00007
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Published: Ann Intern Med. 2007;147(3):180-186.
This update in clinical cardiology focuses on topics of interest and importance to practicing internists. The Table summarizes conclusions to consider for your practice.
Occluded Artery Trial Investigators.
Question: Does percutaneous coronary intervention (PCI) reduce the incidence of adverse cardiovascular events in patients with myocardial infarction who present after 72 hours?
Study Design: Randomized, controlled trial.
Patients: 2166 patients who presented 3 to 28 days after an acute myocardial infarction with total occlusion of the infarct-related artery. The following were excluded: patients with New York Heart Association (NYHA) classification III or IV heart failure, shock, a serum creatinine concentration greater than 2.5 mg/dL (>221 µmol/L), angiographically significant left-main or 3-vessel coronary artery disease, angina at rest, or severe ischemia on stress testing (required if the infarct zone was not akinetic or dyskinetic).
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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