Luis Maillo, MD
Potential Financial Conflicts of Interest: None disclosed.
Maillo L.; Anaphylactic Shock with Multiorgan Failure in a Cyclist after Intravenous Administration of Actovegin. Ann Intern Med. 2008;148:407. doi: 10.7326/0003-4819-148-5-200803040-00022
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Published: Ann Intern Med. 2008;148(5):407.
Background: Actovegin (Nycomed Pharma, Zurich, Switzerland) is a calf-blood extract free of proteins and filtrated to remove prions. It is marketed in some countries for the treatment of cerebrovascular and metabolic disorders, peripheral flow disorders, burns, and wounds (1–4) and is used by some athletes to improve blood oxygenation without raising hematocrit, purportedly by promoting glucose and oxygen uptake by cells (5, 6). Actovegin has been banned by the International Olympics Committee since 2000.
Objective: To report a case of anaphylaxis with use of Actovegin.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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