Jennifer A. Curry, MD; Nehkonti Adams, MD; Nancy F. Crum-Cianflone, MD, MPH
Note: The opinions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Departments of the Army, Navy, or Air Force or the Department of Defense. The authors have no commercial or other association that might pose a conflict of interest in this work. This work is original and has not been published elsewhere.
Grant Support: By the Infectious Disease Clinical Research Program (IDCRP), Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD, of which the TriService AIDS Clinical Consortium is a component. The IDCRP is a Department of Defense tri-service program executed through USUHS and the Henry M. Jackson Foundation for the Advancement of Military Medicine in collaboration with the Department of Health and Human Services/National Institutes of Health/National Institute of Allergy and Infectious Diseases/Department of Conservation and Recreation through Interagency Agreement HU0001-05-2-0011.
Potential Financial Conflicts of Interest: None disclosed.
Curry JA, Adams N, Crum-Cianflone NF. Acute Hepatitis E Virus Infection in an HIV-Infected Person in the United States. Ann Intern Med. 2009;150:226-227. doi: 10.7326/0003-4819-150-3-200902030-00028
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Published: Ann Intern Med. 2009;150(3):226-227.
Background: Hepatitis E virus (HEV) is an enterically transmitted cause of viral hepatitis that is rarely noted without international travel.
Objective: To report the first case of an HIV-infected man with acute hepatitis due to HEV infection who had not traveled outside the United States.
Case Report: A 45-year-old HIV-positive man had mildly elevated aminotransferase levels that were asymptomatic. He had a CD4 cell count of 0.36 × 109 cells/L (31%) with undetectable HIV RNA (<50 copies/mL) while receiving abacavir–lamivudine, atazanavir, and ritonavir. He had visited Maine and Illinois 4 weeks previously but reported no exposure to sick persons, nonmunicipal water, or farm animals; international travel; or medication changes. He reported having had anonymous sexual partners but did not report alcohol or illicit drug use.
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