Harold C. Sox, MD, Editor; Sheldon Greenfield, MD
Sox HC, Greenfield S. Comparative Effectiveness Research: A Report From the Institute of Medicine. Ann Intern Med. 2009;151:203-205. doi: 10.7326/0003-4819-151-3-200908040-00125
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Published: Ann Intern Med. 2009;151(3):203-205.
CER is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat and monitor a clinical condition, or to improve the delivery of care. The purpose of CER is to assist consumers, clinicians, purchasers, and policy makers to make informed decisions that will improve health care at both the individual and population levels.
The CER Program should develop strategies to reach out to, engage, support, educate, and, as necessary, prepare consumers, patients and their caregivers for leadership roles in these activities.
The CER Program should also encourage broad participation in CER research in order to create a representative evidence base that could help identify health disparities and inform decisions by patients in special population groups.
The CER Program should ensure that CER researchers and institutions implement privacy and security protections in all their activities.
The CER Program should support the development of methodologies for linking patient-level data from multiple sources, and for analyzing the resulting data for CER.
The CER Program should promote widespread participation and provide incentives to data holders to participate in CER.
Development of a strategic plan for research workforce development.
Long-term, sufficient funding for career development including expanding grants for graduate and postgraduate training opportunities in comparative effectiveness methods as well as career development grants and mid-career merit awards.
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