Alan N. Barkun, MD, MSc (Clinical Epidemiology); Marc Bardou, MD, PhD; Ernst J. Kuipers, MD; Joseph Sung, MD; Richard H. Hunt, MD; Myriam Martel, BSc; Paul Sinclair, MSc; International Consensus Upper Gastrointestinal Bleeding Conference Group
Note: This consensus conference, organized by the Canadian Association of Gastroenterology, was held in Vienna, Austria, on 23–24 October 2008. These consensus recommendations are endorsed by the Canadian Association of Gastroenterology, the Asian Pacific Society of Digestive Endoscopy, and the European Association for Gastroenterology and Endoscopy. Since the consensus conference, the following professional societies have reviewed and also endorsed the recommendations: European Society of Gastrointestinal Endoscopy, Hong Kong Society of Digestive Endoscopy, Italian Society of Digestive Endoscopy, Asociación Española de Gastroenterología, Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas, and Sociedad de Gastroenterologia del Uruguay.
Acknowledgment: The authors thank Pauline Lavigne for editorial assistance; Anoush Rhazzagi, Alexandra Shingina, and Aurélie Fichet for research assistance; and Sandra Daniels and Andres Gardeazabal for organization of the consensus conference.
Grant Support: By the Canadian Association of Gastroenterology; European Association for Gastroenterology and Endoscopy; Asian Pacific Society of Digestive Endoscopy; and Institute of Diabetes, Metabolism, and Nutrition (of the Canadian Institutes of Health Research), and at-arms-length contributions to these societies from AstraZeneca Mölndal, Abbott Canada, and Olympus Canada.
Potential Conflicts of Interest:Consultancies: A.N. Barkun (Astra Zeneca), R.H. Hunt (Schering-Plough), P. Sinclair (AstraZeneca). Honoraria: M. Bardou (AstraZeneca), E.J. Kuipers (AstraZeneca), J. Sung (Nycomed), R.H. Hunt (Nycomed). Grants pending: A.N. Barkun (AstraZeneca, Olympus), E.J. Kuipers (AstraZeneca), J. Sung (AstraZeneca). Patents pending: A.N. Barkun (Abbott). Other: E.J. Kuipers (AstraZeneca).
Requests for Single Reprints: Alan Barkun, MD, MSc (Clinical Epidemiology), Division of Gastroenterology, Montreal General Hospital Site, The McGill University Health Centre, 1650 Cedar Avenue, Room D7.148, Montreal, Quebec H3G 1A4, Canada.
Current Author Addresses: Dr. Barkun: Division of Gastroenterology, Montreal General Hospital Site, The McGill University Health Centre, 1650 Cedar Avenue, Room D7.148, Montreal, Quebec H3G 1A4, Canada.
Dr. Bardou: INSERM CIC-P 803, CHU de Dijon, 2 boulevard de Lattre de Tassigny, 21000 Dijon, France.
Dr. Kuipers: Erasmus University Medical Centre, Room Ba-391, Box 2040, 3000 CA Rotterdam, the Netherlands.
Dr. Sung: Department of Medicine and Therapeutics, 9/F Clinical Science Building, Prince of Wales Hospital, Chinese University of Hong Kong, Sha Tin NT, Hong Kong.
Dr. Hunt: Division of Gastroenterology, McMaster University Health Science Centre, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.
Ms. Martel: 1299 Rue Prospect, Sherbrooke, Quebec J1J 1J4, Canada.
Mr. Sinclair: Canadian Association of Gastroenterology, #224, 1540 Cornwall Road, Oakville, Ontario L6J 7W5, Canada.
Author Contributions: Conception and design: A.N. Barkun, E.J. Kuipers, J. Sung, P. Sinclair.
Analysis and interpretation of the data: A.N. Barkun, M. Bardou, E.J. Kuipers, J. Sung, R.H. Hunt, M. Martel, P. Sinclair.
Drafting of the article: A.N. Barkun, E.J. Kuipers, J. Sung, R.H. Hunt, P. Sinclair.
Critical revision of the article for important intellectual content: A.N. Barkun, M. Bardou, J. Sung, P. Sinclair.
Final approval of the article: A.N. Barkun, M. Bardou, E.J. Kuipers, J. Sung, R.H. Hunt, P. Sinclair.
Provision of study materials or patients: J. Sung.
Statistical expertise: A.N. Barkun, M. Martel.
Obtaining of funding: E.J. Kuipers, P. Sinclair.
Administrative, technical, or logistic support: A.N. Barkun, E.J. Kuipers, P. Sinclair.
Collection and assembly of data: M. Bardou, E.J. Kuipers, M. Martel, P. Sinclair.
For a list of voting participants, see Appendix 1.
Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, et al. International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding. Ann Intern Med. 2010;152:101-113. doi: 10.7326/0003-4819-152-2-201001190-00009
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Published: Ann Intern Med. 2010;152(2):101-113.
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