Marion L. Vetter, MD, RD; Nayyar Iqbal, MD, MSCE; Cornelia Dalton-Bakes, BS; Sheri Volger, MS, RD; Thomas A. Wadden, PhD
Potential Conflicts of Interest: None disclosed.
Vetter M., Iqbal N., Dalton-Bakes C., Volger S., Wadden T.; Long-Term Effects of Low-Carbohydrate Versus Low-Fat Diets in Obese Persons. Ann Intern Med. 2010;152:334-335. doi: 10.7326/0003-4819-152-5-201003020-00020
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Published: Ann Intern Med. 2010;152(5):334-335.
Background: We reported elsewhere (1) the results of a randomized, controlled trial that found greater weight loss at 6 months with a low-carbohydrate diet (<30 g/d) than with a calorie-restricted, low-fat diet (deficit of 500 kcal/d with <30% kcal from fat) in 132 participants with a mean weight of 130.9 kg (SD, 25.2) and a high prevalence of diabetes and the metabolic syndrome. We subsequently reported (2) no significant differences in weight loss between groups at the end of the trial (12 months).
Objective: To assess outcomes after 36 months.
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