Mark J. Pletcher, MD, MPH; Pamela G. Coxson, PhD
Potential Conflicts of Interest: None disclosed.
Pletcher MJ, Coxson PG. Does Age Modify Effectiveness of Statin Therapy in Coronary Artery Disease?. Ann Intern Med. 2010;152:825. doi: 10.7326/0003-4819-152-12-201006150-00018
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Published: Ann Intern Med. 2010;152(12):825.
TO THE EDITOR:
Hayward and colleagues (1) presented a modeling analysis comparing the total effect and efficiency of a completely risk-based “tailored-treatment” strategy with a traditional National Cholesterol Education Program (NCEP)–based “treat-to-target” strategy. As noted by the authors, treatment benefit in any given person is a function of his or her baseline risk and the relative risk reduction of therapy. The authors then state that “ … we know of no evidence that any single CAD [coronary artery disease] risk factor or biomarker helps predict the relative effectiveness of starting statin therapy.”
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