Ken K.Y. Ho, MD; Udo Meinhardt, MD; David Clifford, PhD
Potential Conflicts of Interest: None disclosed.
Ho K., Meinhardt U., Clifford D.; Misleading Interpretations and Public Misinformation on Human Growth Hormone in Athletes. Ann Intern Med. 2010;153:346-347. doi: 10.7326/0003-4819-153-5-201009070-00015
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Published: Ann Intern Med. 2010;153(5):346-347.
Mr. Sorensen and Dr. Tobias and colleagues voice concerns about the interpretation and media communication of our findings, focusing on a sentence in the Discussion section of our article. The issue centers on what an improvement in Wingate performance means.
Wingate test performance depends on all available forms of muscle energy supply and is primarily a measure of power and anaerobic capacity (1). In the context of the broad performance categories assessed in our study, it is the form of testing that is most closely aligned to sprint events (rather than endurance running, weightlifting, or high jump). We did not state that the Wingate test and sprint capacity are “equivalent measures,” as Mr. Sorensen says. Although strength and power are determinants of sprint capacity (2), we found no evidence that either was enhanced by growth hormone, leading us to postulate that the anaerobic energy required to drive contractile muscle function may be increased by growth hormone. Indeed, several studies (3, 4) have shown a positive relationship between Wingate anaerobic capacity and sprint performance.
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