John F. Deeken, MD; Louis M. Weiner, MD
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-1941.
Requests for Single Reprints: Louis M. Weiner, MD, Lombardi Comprehensive Cancer Center, 501 New Research Building, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007; e-mail, firstname.lastname@example.org.
Current Author Addresses: Dr. Weiner: Lombardi Comprehensive Cancer Center, 501 New Research Building, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007.
Dr. Deeken: Podium B, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007.
Deeken J., Weiner L.; Supportive Treatments for Oncology Patients: Not Just Icing on the Cake. Ann Intern Med. 2010;153:411-412. doi: 10.7326/0003-4819-153-6-201009210-00010
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Published: Ann Intern Med. 2010;153(6):411-412.
Oral mucositis is a frequent and debilitating complication of cancer chemotherapy and radiation therapy. The symptoms range from mild odynophagia to severe tissue inflammation, edema, and mucosal bleeding that can make eating impossible and—in its most severe form—necessitate intubation to protect a patient's airway. A vicious cycle can ensue as patients experience progressive mucositis during treatment, with worsening pain and dysphagia leading to reduced oral intake and resulting in malnutrition, weight loss, fatigue, and deconditioning. Oral ulcers also increase the risk for bacterial and fungal colonization and for systemic infection in immunocompromised patients (1).
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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