James Douketis, MD; Alberto Tosetto, MD; Maura Marcucci, MD; Trevor Baglin, MD, PhD; Mary Cushman, MD, MSc; Sabine Eichinger, MD; Gualtiero Palareti, MD, PhD; Daniela Poli, MD; R. Campbell Tait, MBChB; Alfonso Iorio, MD
Acknowledgment: The authors thank Dr. Clive Kearon for his review of the manuscript.
Grant Support: The source studies were funded by the FCSA (Italian Federation of Anticoagulation Clinics); Oesterreichische Nationalbank (Jubilaeumsfonds); Medizinisch-Wissenschaftlicher Fonds des Buergermeisters der Bundeshauptstadt Wien; Wiener Staedtische Versicherung; Scottish Government Health Department (Chief Scientist grant CZB/4/24); and the National Heart, Lung, and Blood Institute (grants HL-57951 and HL-58036).
Potential Conflicts of Interest: Dr. Tosetto: Travel/accommodations/meeting expenses unrelated to activities listed: NovoNordisk, Instrumentation Laboratories. Dr. Cushman: Grants received: National Heart, Lung, and Blood Institute. Dr. Eichinger: Payment for lectures, including service on speakers bureaus: Boehringer Ingelheim, Bayer, Siemens Healthcare, Pfizer. Dr. Palareti: Grants received (to institution): FCSA (Italian Federation of Anticoagulation Clinics). Payment for lectures, including service on speakers bureaus: Instrumentation Laboratory, Siemens, Bayer, Sanofi-Aventis, Boehringer Ingelheim. Dr. Tait: Grants received (to institution): Scottish Government Health Department. Dr. Iorio: Board membership: Pfizer, Baxter, NovoNordisk. Consultancy: Pfizer. Payment for lectures, including service on speakers bureaus: Pfizer, Baxter, Bayer, NovoNordisk. Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-0798.
Requests for Single Reprints: James Douketis, MD, St. Joseph's Healthcare Hamilton, Room F-544, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada; e-mail, email@example.com.
Current Author Addresses: Dr. Douketis: St. Joseph's Healthcare Hamilton, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada.
Dr. Tosetto: Division of Hematology, Ospedale San Bortolo, via Rodolfi 37, 36100 Vicenza, Italy.
Dr. Marcucci: Department of Medicine, University of Perugia, via Dottori 1, 06156 Perugia, Italy.
Dr. Baglin: Cambridge University Hospitals National Health Service Trust, Department of Haematology, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom.
Dr. Cushman: Department of Medicine, University of Vermont, 208 South Park Drive, Colchester, VT 05446.
Dr. Eichinger: Department of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
Dr. Palareti: Department of Angiology and Blood Coagulation, University Hospital of Bologna, Bologna, Italy.
Dr. Poli: Department of Heart and Vessels, Centro di Riferimento Regionale per la Trombosi, Azienda Ospedaliero-Universitaria Careggi, via le Morgagni 85, 50134 Florence, Italy.
Dr. Tait: Department of Haematology, Macewen Building, 3rd Floor, Royal Infirmary, Castle Street, Glasgow G4 0SF, United Kingdom.
Dr. Iorio: Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.
Author Contributions: Conception and design: J. Douketis, A. Tosetto, M. Cushman, S. Eichinger, A. Iorio.
Analysis and interpretation of the data: J. Douketis, A. Tosetto, M. Marcucci, T. Baglin, S. Eichinger, A. Iorio.
Drafting of the article: J. Douketis, M. Marcucci, T. Baglin, S. Eichinger.
Critical revision of the article for important intellectual content: J. Douketis, A. Tosetto, M. Marcucci, T. Baglin, M. Cushman, S. Eichinger, D. Poli, R.C. Tait, A. Iorio.
Final approval of the article: J. Douketis, A. Tosetto, M. Marcucci, T. Baglin, M. Cushman, S. Eichinger, G. Palareti, D. Poli, R.C. Tait, A. Iorio.
Provision of study materials or patients: M. Cushman, S. Eichinger, G. Palareti, D. Poli, R.C. Tait.
Statistical expertise: M. Marcucci, A. Iorio.
Administrative, technical, or logistic support: J. Douketis, M. Cushman, S. Eichinger.
Collection and assembly of data: J. Douketis, M. Marcucci, T. Baglin, M. Cushman, S. Eichinger, R.C. Tait, A. Iorio.
Douketis J, Tosetto A, Marcucci M, Baglin T, Cushman M, Eichinger S, et al. Patient-Level Meta-analysis: Effect of Measurement Timing, Threshold, and Patient Age on Ability of d-Dimer Testing to Assess Recurrence Risk After Unprovoked Venous Thromboembolism. Ann Intern Med. 2010;153:523-531. doi: 10.7326/0003-4819-153-8-201010190-00009
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Published: Ann Intern Med. 2010;153(8):523-531.
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