Robert F. Schilling, MD
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Schilling RF. Tripping on the HIPAA Hurdle. Ann Intern Med. 2011;154:133-134. doi: 10.7326/0003-4819-154-2-201101180-00015
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Published: Ann Intern Med. 2011;154(2):133-134.
In 1954, a boy aged 16 years was referred to our institution for evaluation of hemolytic anemia. Spherocytes were seen on his blood film. Five of his 6 siblings also had evidence of hemolytic spherocytosis. Although neither parent had clinical or laboratory evidence of hemolysis or spherocytosis, the condition was obviously inherited because a paternal aunt had been cured of hemolytic anemia by splenectomy. I was intrigued by the variable manifestations of disease in the family and made hereditary spherocytosis a continuing area of investigation. Over the next half-century, my colleagues and I collected clinical data from approximately 700 affected and nonaffected members in 35 putatively unrelated kindreds.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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