Caroline Minassian, MSc; Liam Smeeth, PhD; Francesco D'Aiuto, PhD; Aroon D. Hingorani, PhD
Potential Conflicts of Interest: Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-0574.
Minassian C., Smeeth L., D'Aiuto F., Hingorani A.; Invasive Dental Treatment and Risk for Vascular Events. Ann Intern Med. 2011;154:442. doi: 10.7326/0003-4819-154-6-201103150-00016
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Published: Ann Intern Med. 2011;154(6):442.
We are pleased that our study on the risk for vascular events after invasive dental treatment has generated interest. However, it is clear that some readers poorly understood this study, and we would like to address some of the points that they raised.
Dr. Janket and colleagues may have misinterpreted the SCCS method that we used as a collection of case reports with no comparison group. We agree that such uncontrolled case series could be prone to confounding and are unsuitable for investigating causal relationships. Readers should not confuse this method with the SCCS method that we used, which provides an alternative to the more established cohort method for estimating the relative incidence of an event.
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