Neiha Arora, MD; Glenn M. Chertow, MD, MPH
Article relevant to primary care general internists
Article relevant to hospitalists
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M11-0462.
Requests for Single Reprints: Glenn M. Chertow, MD, MPH, Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Suite 106, Palo Alto, CA 94034; e-mail, email@example.com.
Current Author Addresses: Drs. Chertow and Arora: Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Suite 106, Palo Alto, CA 94034.
Author Contributions: Conception and design: G.M. Chertow, N. Arora.
Analysis and interpretation of the data: G.M. Chertow, N. Arora.
Drafting of the article: G.M. Chertow, N. Arora.
Critical revision of the article for important intellectual content: G.M. Chertow, N. Arora.
Final approval of the article: G.M. Chertow, N. Arora.
Administrative, technical, or logistic support: G.M. Chertow, N. Arora.
Collection and assembly of data: G.M. Chertow, N. Arora.
Arora N, Chertow GM. Update in Nephrology: Evidence Published in 2010. Ann Intern Med. 2011;154:824-829. doi: 10.7326/0003-4819-154-12-201106210-00342
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Published: Ann Intern Med. 2011;154(12):824-829.
A landmark year in nephrology, 2010 saw the publication of many large (and small), simple (and focused) randomized, controlled trials in areas of fundamental importance to both nephrologists and general internists. Some trials showed no benefit of interventions that many clinicians had previously assumed to be so. These “negative” trials inform practice in important ways. Other trials showed benefit or harm, but issues of external validity should temper these findings. Large, high-quality cohort studies continued to build evidence on which to base practice. Finally, innovative basic science and genetic studies have begun to offer insight about differences in the clinical manifestations of kidney disease across the population. Here, we summarize what we believe to be the 10 most clinically important studies published in 2010. These studies address 6 key areas: hypertension, nephrolithiasis, chronic kidney disease (CKD), dialysis, transplantation, and acute kidney injury (AKI).
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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