Phuc Le; Michael B. Rothberg
Herpes zoster vaccine is licensed for persons aged 50 years or older, but the Advisory Committee on Immunization Practices (ACIP) recommends it only for those aged 60 years or older. This analysis evaluated the cost-effectiveness of herpes zoster vaccine versus no vaccination among adults aged 50 years. Their results support the ACIP recommendation that herpes zoster vaccine be used only in persons aged 60 years or older.
Ann Intern Med. 2015;163(7):489-497. doi:10.7326/M15-0093
Patrick S. Twomey; Bryan L. Smith; Cathy McDermott; Anne Novitt-Moreno; William McCarthy; S. Patrick Kachur; Paul M. Arguin
Quinidine gluconate, the only drug approved for treatment of severe malaria in the United States, has substantial adverse effects and limited availability. In a program administered by the Centers for Disease Control and Prevention, intravenous artesunate seemed to be a safe and effective alternative to quinidine for the treatment of life-threatening malaria.
Ann Intern Med. 2015;163(7):498-506. doi:10.7326/M15-0910
Michael J. Silverberg; Bryan Lau; Chad J. Achenbach; Yuezhou Jing; Keri N. Althoff; Gypsyamber D'Souza; Eric A. Engels; Nancy A. Hessol; John T. Brooks; Ann N. Burchell; M. John Gill; James J. Goedert; Robert Hogg; Michael A. Horberg; Gregory D. Kirk; Mari M. Kitahata; Philip T. Korthuis; William C. Mathews; Angel Mayor; Sharada P. Modur; Sonia Napravnik; Richard M. Novak; Pragna Patel; Anita R. Rachlis; Timothy R. Sterling; James H. Willig; Amy C. Justice; Richard D. Moore; Robert Dubrow;
Cancer has become more common among persons with HIV. After examination of cumulative cancer incidence by age 75 years and calendar trends in cumulative incidence and hazard rates, it was determined that the cumulative incidences of anal, colorectal, and liver cancer are increasing among persons with HIV because they are living longer. The highest cumulative incidences were seen for Kaposi sarcoma, non-Hodgkin lymphoma, and lung cancer.
Ann Intern Med. 2015;163(7):507-518. doi:10.7326/M14-2768
Reed A.C. Siemieniuk; Maureen O. Meade; Pablo Alonso-Coello; Matthias Briel; Nathan Evaniew; Manya Prasad; Paul E. Alexander; Yutong Fei; Per O. Vandvik; Mark Loeb; Gordon H. Guyatt
This meta-analysis of 13 randomized trials examines the benefits and harms of adjunctive, systemic corticosteroid therapy for adults hospitalized with community-acquired pneumonia. It found that systemic corticosteroid therapy may reduce mortality by approximately 3%, need for mechanical ventilation by approximately 5%, and hospital stay by approximately 1 day.
Ann Intern Med. 2015;163(7):519-528. doi:10.7326/M15-0715
Holger J. Schünemann; Lubna A. Al-Ansary; Frode Forland; Sonja Kersten; Jorma Komulainen; Ina B. Kopp; Fergus Macbeth; Susan M. Phillips; Craig Robbins; Philip van der Wees; Amir Qaseem;
In response to requests from its international membership and informed by existing syntheses of the evidence and policies of international organizations, the Guidelines International Network Board of Trustees developed guidance on the disclosure and management of conflicts of interest in the context of guideline development.
Ann Intern Med. 2015;163(7):548-553. doi:10.7326/M14-1885
Risa B. Burns; Jennifer E. Potter; Hope A. Ricciotti; Eileen E. Reynolds
The American College of Physicians recommends against routine annual pelvic examination in adult, asymptomatic women at average risk; the American College of Obstetrics and Gynecology recommends in favor of routine annual pelvic examination. This paper summarizes a discussion between an internist and a gynecologist on how they would balance recommendations in general and what they would suggest for an individual patient.
Ann Intern Med. 2015;163(7):537-547. doi:10.7326/M15-1220
Albert L. Siu;
This 2015 recommendation statement by the U.S. Preventive Services Task Force addresses screening for iron deficiency anemia and routine iron supplementation in pregnant women. Recommendations are based on whether screening or routine supplementation improves maternal and birth outcomes.
Ann Intern Med. 2015;163(7):529-536. doi:10.7326/M15-1707
The ICD-10 becomes a legal standard for diagnosis coding in the United States on 1 October 2015. This commentary explains why it is time to move to the ICD-10.
Ann Intern Med. 2015;163(7):557-558. doi:10.7326/M15-1773
Brian Outland; Mary M. Newman; Margo J. William
The United States will transition to the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10), on 1 October 2015. This article outlines the implications of moving to ICD-10 and recommends resources to facilitate the transition.
Ann Intern Med. 2015;163(7):554-556. doi:10.7326/M15-1933
Ann Intern Med. 2015;163(7):559. doi:10.7326/M15-1073
Marcos I. Restrepo; Antonio Anzueto; Antoni Torres
This issue contains a systematic review and meta-analysis of 13 randomized, controlled trials of adjunctive therapy with systemic corticosteroids versus placebo for patients hospitalized with community-acquired pneumonia. The editorialists discuss the review and call for changes in clinical practice.
Ann Intern Med. 2015;163(7):560-561. doi:10.7326/M15-1805
George A. Sarosi
Fans of the “Prairie Home Companion” probably believe that Minnesota is densely populated with Norwegian bachelor farmers. However, I never met one until Mr. O was admitted to my medical service.
Ann Intern Med. 2015;163(7):562-563. doi:10.7326/M15-1202
Ann Intern Med. 2015;163(7):564. doi:10.7326/L15-5141
Ann Intern Med. 2015;163(7):564-565. doi:10.7326/L15-5141-2
Ann Intern Med. 2015;163(7):565. doi:10.7326/L15-5142
Ann Intern Med. 2015;163(7):565-566. doi:10.7326/L15-5142-2
Ann Intern Med. 2015;163(7):566. doi:10.7326/L15-5144
Ann Intern Med. 2015;163(7):566-567. doi:10.7326/L15-5144-2
Ann Intern Med. 2015;163(7):567-568. doi:10.7326/L15-5145
Ann Intern Med. 2015;163(7):536. doi:10.7326/M15-1467
Ann Intern Med. 2015;163(7):553. doi:10.7326/M15-0226
Ann Intern Med. 2015;163(7):563. doi:10.7326/M15-1470
Michael S. Niederman
Ann Intern Med. 2015;163(7):ITC1. doi:10.7326/AITC201510060
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2015;163(7):W141-W145. doi:10.7326/G15-0003
Ann Intern Med. 2015;163(7):I-23. doi:10.7326/P15-9030
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