Joshua M. Thorpe, PhD, MPH; Carolyn T. Thorpe, PhD, MPH; Walid F. Gellad, MD, MPH; Chester B. Good, MD, MPH; Joseph T. Hanlon, PharmD, MS; Maria K. Mor, PhD; John R. Pleis, MS; Loren J. Schleiden, BS; Courtney Harold Van Houtven, PhD
Recent federal policy changes that have expanded veterans' access to care outside the Department of Veterans Affairs (VA) may have unintended consequences on safe and effective prescribing. This study examined the prevalence and effect of dual use of VA and Medicare Part D prescription benefits on prescribing safety among a national cohort of veteran outpatients with dementia.
Ann Intern Med. 2017;166(3):157-163. doi:10.7326/M16-0551
Christopher M. Callahan, MD; Malaz A. Boustani, MD, MPH; Arlene A. Schmid, PhD, OTR; Michael A. LaMantia, MD, MPH; Mary G. Austrom, PhD; Douglas K. Miller, MD; Sujuan Gao, PhD; Denisha Y. Ferguson, AAS; Kathleen A. Lane, MS; Hugh C. Hendrie, MB ChB, DSc
Functional decline from Alzheimer disease has profound negative consequences for both patients and their caregivers. A randomized, controlled trial conducted among community-dwelling patients with Alzheimer disease assessed the effects of a 2-year, home-based, occupational therapy intervention on measures related to activities of daily living, physical performance, and sarcopenia.
Ann Intern Med. 2017;166(3):164-171. doi:10.7326/M16-0830
Craig Garthwaite, PhD; Tal Gross, PhD; Matthew Notowidigdo, PhD; John A. Graves, PhD
Health policy analysts did not know how patients might change the way they use emergency departments (EDs) when the Patient Protection and Affordable Care Act (ACA) was introduced in January 2014. The investigators of this study examined the records of adults who went to hospital EDs before and after the ACA took effect. They found changes in the frequency of visits by uninsured and Medicaid-insured patients and changes in travel time to the ED in 17 Medicaid expansion states but not in 19 nonexpansion states.
Ann Intern Med. 2017;166(3):172-179. doi:10.7326/M16-0086
Casey N. McQuade, MD; Marisa Mizus, MD, MS; Joyce W. Wald, DO; Lee Goldberg, MD, MPH; Mariell Jessup, MD; Craig A. Umscheid, MD, MSCE
This meta-analysis of trials and observational studies addresses the clinical implications of achieving predischarge natriuretic peptide thresholds in patients hospitalized for acute decompensated heart failure.
Ann Intern Med. 2017;166(3):180-190. doi:10.7326/M16-1468
Matthew J. Crowley, MD, MHS; Clarissa J. Diamantidis, MD, MHS; Jennifer R. McDuffie, PhD; C. Blake Cameron, MD, MBI; John W. Stanifer, MD, MSc; Clare K. Mock, MD; Xianwei Wang, MD; Shuang Tang, PhD; Avishek Nagi, MS; Andrzej S. Kosinski, PhD; John W. Williams Jr., MD, MHS
This systematic review of 17 observational studies addresses clinical outcomes of metformin use in persons with type 2 diabetes and moderate to severe chronic kidney disease, congestive heart failure, or chronic liver disease with hepatic impairment. These major findings, which support recent labeling changes by the U.S. Food and Drug Administration, have important clinical implications.
Ann Intern Med. 2017;166(3):191-200. doi:10.7326/M16-1901
Howard Libman, MD; Diane M. Brockmeyer, MD; Howard S. Gold, MD
This Grand Rounds summarizes a discussion between 2 expert clinicians about the benefits and harms of prescribing antibiotics to a patient with recurrent sinusitis presenting with persistent upper respiratory symptoms.
Ann Intern Med. 2017;166(3):201-208. doi:10.7326/M16-2766
David K. Kim, MD, MA; Laura E. Riley, MD; Kathleen H. Harriman, PhD, MPH, RN; Paul Hunter, MD; Carolyn B. Bridges, MD; on behalf of the Advisory Committee on Immunization Practices
The Advisory Committee on Immunization Practices (ACIP) presents the Recommended Adult Immunization Schedule for Adults Aged 19 Years or Older for 2017. This schedule has been approved by the ACIP, American College of Physicians, American Academy of Family Physicians, American College of Obstetricians and Gynecologists, and American College of Nurse-Midwives.
Ann Intern Med. 2017;166(3):209-219. doi:10.7326/M16-2936
Daniel M. Blumenthal, MD, MBA; Dana P. Goldman, PhD; Anupam B. Jena, MD, PhD
Insurers are increasingly tying reimbursement to patient outcomes to promote accountability for care, but this has largely not been the case for biopharmaceuticals despite their growing use and high costs. This commentary discusses the potential benefits of outcomes-based pricing as a means of promoting access to novel biopharmaceuticals and ensuring that manufacturers and insurers are both accountable for clinical outcomes.
Ann Intern Med. 2017;166(3):219-220. doi:10.7326/M16-1847
David R. Gifford, MD, MPH
Thorpe and colleagues report that patients with dementia who had access to medications both within and outside of the VA system were more likely than those with access only within the VA system to receive medications associated with an increased risk for adverse events. The editorialist discusses these findings and argues that sometimes the U.S. health care system's prioritization of choice over coordination does not serve patients well.
Ann Intern Med. 2017;166(3):221-222. doi:10.7326/M16-2590
G. Michael Felker, MD, MHS; David J. Whellan, MD, MHS
McQuade and colleagues present the current evidence on natriuretic peptides (NPs) as markers of readiness for hospital discharge in patients with heart failure. The editorialists discuss the findings and the steps necessary to define the role of NPs in decision making with regard to the management of heart failure.
Ann Intern Med. 2017;166(3):223-224. doi:10.7326/M16-2667
Kasia J. Lipska, MD, MHS
Crowley and colleagues report a systematic review of metformin and its effect on several relevant clinical outcomes. The editorialist discusses the findings of that review. Because metformin is widely used and inexpensive, a better understanding of its effect on outcomes in contemporary practice, as well as among subgroups of patients with common comorbid conditions, is imperative.
Ann Intern Med. 2017;166(3):225-226. doi:10.7326/M16-2712
Frederick W. Hund, MD
Ann Intern Med. 2017;166(3):227-228. doi:10.7326/M16-1241
Ann Intern Med. 2017;166(3):229. doi:10.7326/L16-0627
Ann Intern Med. 2017;166(3):229-230. doi:10.7326/L16-0628
Ann Intern Med. 2017;166(3):230. doi:10.7326/L16-0629
Ann Intern Med. 2017;166(3):230-231. doi:10.7326/L16-0622
Ann Intern Med. 2017;166(3):231-232. doi:10.7326/L16-0621
Ann Intern Med. 2017;166(3):232. doi:10.7326/L16-0638
Karen R. Jacobson, MD, MPH
Ann Intern Med. 2017;166(3):ITC17-ITC32. doi:10.7326/AITC201702070
Darren B. Taichman, MD, PhD
Ann Intern Med. 2017;166(3):ED3. doi:10.7326/AFED201702070
Steven Breecker, MD
Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video.
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0013
David Cognetti, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0014
Abigail Kay, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0015
Rosalind Kaplan, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0016
Abigail Wolf, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0017
Mitchell J. Cohen, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0018
Katherine Sherif, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0019
Leo C. Katz, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0020
Traci Trice, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0021
James D. Plumb, MD, MPH
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0022
Steven K. Herrine, MD
Ann Intern Med. 2017;166(3):SS1. doi:10.7326/W17-0023
Satyajeet Roy, MD
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2017;166(3):W3-W4. doi:10.7326/G16-0025
Ann Intern Med. 2017;166(3):I-24. doi:10.7326/P16-9026
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