Anne L. Stephenson, MD, PhD; Jenna Sykes, MMath; Sanja Stanojevic, PhD; Bradley S. Quon, MD, MSc; Bruce C. Marshall, MD; Kristofer Petren, BA, BSc; Josh Ostrenga, MSc; Aliza K. Fink, DSc; Alexander Elbert, PhD; Christopher H. Goss, MD, MSc
Previous studies suggested important differences in survival between patients with cystic fibrosis in Canada and those in the United States but were limited by discrepancies in the way national databases have been assembled. This study used comparable data from large Canadian and U.S. registries to better assess differences in survival and variables that might be associated with them.
Ann Intern Med. 2017;166(8):537-546. doi:10.7326/M16-0858
Christelle Nguyen, MD, PhD; Isabelle Boutron, MD, PhD; Gabriel Baron, PhD; Katherine Sanchez, MD; Clémence Palazzo, MD, PhD; Raphaël Benchimol, MD; Guillaume Paris, MD; Étienne James-Belin, MD; Marie-Martine Lefèvre-Colau, MD, PhD; Johann Beaudreuil, MD, PhD; Jean-Denis Laredo, MD, PhD; Anne Béra-Louville, MD; Anne Cotten, MD, PhD; Jean-Luc Drapé, MD, PhD; Antoine Feydy, MD, PhD; Philippe Ravaud, MD, PhD; François Rannou, MD, PhD; Serge Poiraudeau, MD, PhD
Some patients with chronic low back pain have clinical symptoms and findings on magnetic resonance imaging (MRI) scans that are consistent with active discopathy. In this double-blind, randomized trial, the short-term effect of a single intradiscal glucocorticoid injection on low back pain intensity was compared with the effect from discography alone.
Ann Intern Med. 2017;166(8):547-556. doi:10.7326/M16-1700
Megan E. Roerink, MD; Sebastian J.H. Bredie, MD, PhD; Michael Heijnen; Charles A. Dinarello, MD; Hans Knoop, PhD; Jos W.M. Van der Meer, MD, PhD
Few proven effective treatments exist for chronic fatigue syndrome (CFS). This randomized controlled trial evaluated the benefits and harms of anakinra, an interleukin-1–receptor antagonist, for women with CFS and severe fatigue leading to functional impairment.
Ann Intern Med. 2017;166(8):557-564. doi:10.7326/M16-2391
Kirsten Bibbins-Domingo, PhD, MD, MAS; Evelyn Whitlock, MD, MPH; Tracy Wolff, MD, MPH; Quyen Ngo-Metzger, MD, MPH; William R. Phillips, MD, MPH; Karina W. Davidson, PhD, MASc; Alex H. Krist, MD, MPH; Jennifer S. Lin, MD, MCR; Carol M. Mangione, MD, MSPH; Ann E. Kurth, PhD, CNM, MSN, MPH; Francisco A.R. García, MD, MPH; Susan J. Curry, PhD; David C. Grossman, MD, MPH; C. Seth Landefeld, MD; John W. Epling Jr., MD, MSEd; Albert L. Siu, MD, MSPH
This paper describes the principles and considerations that the U.S. Preventive Services Task Force uses to develop recommendations for specific U.S. populations.
Ann Intern Med. 2017;166(8):565-571. doi:10.7326/M16-2656
James J. Chamberlain, MD; William H. Herman, MD, MPH; Sandra Leal, PharmD; Andrew S. Rhinehart, MD; Jay H. Shubrook, DO; Neil Skolnik, MD; Rita Rastogi Kalyani, MD, MHS
The American Diabetes Association annually updates the Standards of Medical Care in Diabetes. This synopsis focuses on the recommendations from the 2017 Standards about pharmacologic approaches to glycemic treatment for type 2 diabetes.
Ann Intern Med. 2017;166(8):572-578. doi:10.7326/M16-2937
Nathalie Wenger, MD; Marie Méan, MD; Julien Castioni, MD; Pedro Marques-Vidal, MD, PhD; Gérard Waeber, MD; Antoine Garnier, MD, MBA
Little current evidence documents how internal medicine residents spend their time at work. This study recorded internal medicine residents' activities at a Swiss teaching hospital and found that they spend more time at work than scheduled. Activities indirectly related to patients predominated, with direct patient care coming in second. About half the workday was spent using a computer.
Ann Intern Med. 2017;166(8):579-586. doi:10.7326/M16-2238
Steffie Woolhandler, MD, MPH; David U. Himmelstein, MD
President Trump has promised universal coverage and reduced deductibles and copayments, all within tight budgetary constraints. That is a tall order, unlikely to be filled by proposals that Republicans have offered thus far. Although these proposals would probably not achieve the president's triple aim—more coverage, better benefits, and lower costs—single-payer reform could.
Ann Intern Med. 2017;166(8):587-588. doi:10.7326/M17-0302
Khameer K. Kidia, MPhil
As he prepares his match list, an international medical student reflects on how possible changes in U.S. immigration policy and the Patient Protection and Affordable Care Act could affect his own future as well as the flow of medical knowledge and talent in and out of the United States.
Ann Intern Med. 2017;166(8):589-590. doi:10.7326/M17-0323
Joshua M. Liao, MD; Catharine B. Stack, PhD
This article aims to help clinicians understand the implications of missing data due to dropout, a common problem that can affect the validity of clinical trial findings. Several analytic methods exist to handle this problem. Understanding the assumptions behind these methods can help clinicians decide whether and how to incorporate clinical trial findings into their own practice.
Ann Intern Med. 2017;166(8):596-598. doi:10.7326/M17-0195
Florian Bruns, MD, MA; Tessa Chelouche, MD
Although Nazi medical authorities are often assumed to have spurned ethics, Nazi-influenced medical ethics became an important part of the curriculum at all German medical schools between 1939 and 1945. This suggests that medical ethics itself can be corrupted and that a political and public realm of reason and humanity may be more vital in preventing immoral medical conduct than formal instruction in medical ethics.
Ann Intern Med. 2017;166(8):591-595. doi:10.7326/M16-2758
Patrick A. Flume, MD; Donald R. VanDevanter, PhD
Stephenson and colleagues report a sobering comparison of cystic fibrosis survival between Canada and the United States, with a marked advantage for Canadians beginning around 1995. The editorialists discuss possible explanations for the survival gap and conclude that differences in the health care systems between the 2 countries are the most likely contributor.
Ann Intern Med. 2017;166(8):599-600. doi:10.7326/M17-0564
David J. Kennedy, MD; Byron J. Schneider, MD
Nguyen and colleagues report a randomized trial of glucocorticoid injection for patients with chronic low back pain associated with active discopathy. The editorialists the trial's authors for avoiding common pitfalls of low back pain research and discuss explanations for the lack of long-term improvement in pain.
Ann Intern Med. 2017;166(8):601-602. doi:10.7326/M17-0556
Stephen E. Wilkinson, MD
Ann Intern Med. 2017;166(8):603-604. doi:10.7326/M16-1521
Ann Intern Med. 2017;166(8):605-606. doi:10.7326/L17-0105
Ann Intern Med. 2017;166(8):605. doi:10.7326/L17-0106
Ann Intern Med. 2017;166(8):606. doi:10.7326/L17-0104
Ann Intern Med. 2017;166(8):606-607. doi:10.7326/L17-0045
Ann Intern Med. 2017;166(8):607-608. doi:10.7326/L17-0044
Ann Intern Med. 2017;166(8):608-609. doi:10.7326/L17-0071
Ann Intern Med. 2017;166(8):608. doi:10.7326/L17-0072
Ann Intern Med. 2017;166(8):609. doi:10.7326/L16-0376
Ann Intern Med. 2017;166(8):610. doi:10.7326/L16-0470
Ann Intern Med. 2017;166(8):610-612. doi:10.7326/L16-0353
Alena Shantsila, MD; Gregory Y.H. Lip, MD
Ann Intern Med. 2017;166(8):JC38. doi:10.7326/ACPJC-2017-166-8-038
René Rodriguez-Gutierrez, MD; Victor M. Montori, MD
Ann Intern Med. 2017;166(8):JC39. doi:10.7326/ACPJC-2017-166-8-039
Donald A. Smith, MD, MPH
Ann Intern Med. 2017;166(8):JC40. doi:10.7326/ACPJC-2017-166-8-040
Dennis G. Maki, MD, MACP
Ann Intern Med. 2017;166(8):JC41. doi:10.7326/ACPJC-2017-166-8-041
Matthew Thompson, MBChB, MPH, DPhil; Terry Scott, MPA, PA-C
Ann Intern Med. 2017;166(8):JC42. doi:10.7326/ACPJC-2017-166-8-042
Angela Lowenstern, MD; L. Kristin Newby, MD, MHS
Ann Intern Med. 2017;166(8):JC43. doi:10.7326/ACPJC-2017-166-8-043
Christopher R. Carpenter, MD, MSc
Ann Intern Med. 2017;166(8):JC44. doi:10.7326/ACPJC-2017-166-8-044
Micelle Haydel, MD, FACEP
Ann Intern Med. 2017;166(8):JC45. doi:10.7326/ACPJC-2017-166-8-045
Sina Jasim, MD, MPH; Steven A Smith, MD
Ann Intern Med. 2017;166(8):JC46. doi:10.7326/ACPJC-2017-166-8-046
Nicholas Talley, MD, PhD, FRACP; Michael Potter, MBBS (Hons)
Ann Intern Med. 2017;166(8):JC47. doi:10.7326/ACPJC-2017-166-8-047
Geno J. Merli, MD; Howard H. Weitz, MD
Annals Consult Guys brings a new perspective to the art and science of medicine with lively discussion and analysis of real-world cases and situations.
Ann Intern Med. 2017;166(8):CG1. doi:10.7326/W17-0004
Darren B. Taichman, MD, PhD
Ann Intern Med. 2017;166(8):ED8. doi:10.7326/AFED201704180
David H. Wesorick, MD; Vineet Chopra, MD, MSc
Ann Intern Med. 2017;166(8):HO1. doi:10.7326/AFHO201704180
Lauren Clack, MSc; Hugo Sax, MD
Ann Intern Med. 2017;166(8):HO2-HO3. doi:10.7326/M17-0544
Ann Intern Med. 2017;166(8):I-18. doi:10.7326/P17-9034
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