Michael Silverman, MD; Marcus Povitz, MDCM, MSc; Jessica M. Sontrop, PhD; Lihua Li, PhD; Lucie Richard, MA; Sonny Cejic, MD; Salimah Z. Shariff, PhD
Reduction of inappropriate antibiotic prescribing for acute upper respiratory tract infections has proven difficult. This retrospective administrative database study examined physician-level variables that predicted inappropriate prescribing of antibiotics to older adults with acute upper respiratory tract infections in Canada.
Ann Intern Med. 2017;166(11):765-774. doi:10.7326/M16-1131
Kathleen N. Ly, MPH; Ruth B. Jiles, PhD, MPH; Eyasu H. Teshale, MD; Monique A. Foster, MD, MPH; Rick L. Pesano, MD, PhD; Scott D. Holmberg, MD, MPH
Hepatitis C virus (HCV) infection is a critical public health threat to young U.S. adults who use drugs. Using 2 large databases, the authors estimated the number of U.S. women of reproductive age with HCV infection from 2011 to 2014 and the subsequent number of HCV-infected babies.
Ann Intern Med. 2017;166(11):775-782. doi:10.7326/M16-2350
Sara Vogrin, MBBS, MBiostat; Richard Harper, MBBS; Elizabeth Paratz, MBBS; Andrew MacIsaac, MBBS; Jodie Burchell, PhD; Belinda Smith, MBBS; Anthony Scott, PhD; Jongsay Yong, PhD; Vijaya Sundararajan, MD, MPH
This study identified the outcomes of patients hospitalized with unstable angina. The investigators compared outcomes of patients who had angiography during their first hospitalization with those of other patients by using advanced statistical methods to adjust for differences in patient characteristics.
Ann Intern Med. 2017;166(11):783-791. doi:10.7326/M16-2420
Susan J. Bersoff-Matcha, MD; Kelly Cao, PharmD; Mihaela Jason, PharmD; Adebola Ajao, PhD; S. Christopher Jones, PharmD, MS, MPH; Tamra Meyer, PhD, MPH; Allen Brinker, MD, MS
Use of direct-acting antivirals (DAAs) to treat patients with hepatitis C virus (HCV) infection has become the standard of care. This report from the U.S. Food and Drug Administration (FDA) focuses on an important safety concern when using DAAs in patients with HCV who are co-infected with hepatitis B.
Ann Intern Med. 2017;166(11):792-798. doi:10.7326/M17-0377
Dennis Anheyer, MA; Heidemarie Haller, MSc; Jürgen Barth, PhD; Romy Lauche, PhD; Gustav Dobos, MD; Holger Cramer, PhD
Mindfulness-based interventions are often used to treat chronic pain. This systematic review and meta-analysis examined the effect of mindfulness-based stress reduction and cognitive therapy programs on pain intensity, pain-related disability, quality of life, and other outcomes among patients with low back pain.
Ann Intern Med. 2017;166(11):799-807. doi:10.7326/M16-1997
Gerald W. Smetana, MD; Daniel B. Jones, MD, MS; Christina C. Wee, MD, MPH
This Grand Rounds summarizes a discussion between a bariatric surgeon and an internist on the pros and cons of weight loss surgery and lifestyle changes, both in general and in the context of a particular patient.
Ann Intern Med. 2017;166(11):808-817. doi:10.7326/M17-0698
Amir Qaseem, MD, PhD, MHA; Mary Ann Forciea, MD; Robert M. McLean, MD; Thomas D. Denberg, MD, PhD; for the Clinical Guidelines Committee of the American College of Physicians
This guideline updates the American College of Physicians' recommendations on treatment of low bone density and osteoporosis to prevent fractures in men and women. It focuses on the comparative benefits and risks of short- and long-term pharmacologic treatments, including pharmaceuticals, calcium, vitamin D, and estrogen.
Ann Intern Med. 2017;166(11):818-839. doi:10.7326/M15-1361
William W. Pinsky, MD
This commentary discusses the current vetting process for international medical graduates and outlines their importance to quality health care delivery in the United States.
Ann Intern Med. 2017;166(11):840-841. doi:10.7326/M17-0505
David Blumenthal, MD, MPP
This commentary discusses the circumstances associated with the creation of electronic patient information, which must be understood and addressed so that all parties contributing to this unparalleled resource are treated fairly.
Ann Intern Med. 2017;166(11):842-843. doi:10.7326/M17-0511
Barbara E. Jones, MD, MSc; Matthew H. Samore, MD
The editorialists discuss Silverman and colleagues' findings and why they believe that the tipping point to a culture of judicious antibiotic use is within reach and that clinicians are at the forefront of change.
Ann Intern Med. 2017;166(11):844-845. doi:10.7326/M17-1061
Alfred DeMaria Jr., MD
Ly and colleagues explore the implications of the current HCV epidemic in reproductive-aged women and their babies. The editorial discusses the consequences of the opioid epidemic on HCV and the need to recognize infection in pregnant women and neonates if HCV is to be eliminated.
Ann Intern Med. 2017;166(11):846-847. doi:10.7326/M17-0927
Sanjit S. Jolly, MD, MSc; P.J. Devereaux, MD, PhD
Vogrin and colleagues reidentify the importance of the question on the effects of an invasive strategy in patients with unstable angina and a negative high-sensitivity troponin measurement. The editorialists advocate for a large, definitive, randomized trial to study this question.
Ann Intern Med. 2017;166(11):848-849. doi:10.7326/M17-0947
Camilla S. Graham, MD, MPH
Authors from the FDA described data submitted to the FDA Adverse Event Reporting System on 29 patients receiving HCV treatment with DAA–based regimens who had reactivation of hepatitis B virus. The editorialist discusses the clinical implications of the findings regarding safety reporting after a drug's approval.
Ann Intern Med. 2017;166(11):850-851. doi:10.7326/M17-0907
Eric S. Orwoll, MD
The editorialist discusses the American College of Physicians' guideline on treatment of low bone density or osteoporosis to prevent fractures and believes that the recommendations provide a solid foundation for informed clinical decisions about individual patients.
Ann Intern Med. 2017;166(11):852-853. doi:10.7326/M17-0957
Elizabeth Chang, MD; Jocelyn Brown, MD, MPH
On a seemingly average emergency room shift, I grab the next chart. When “sexual assault” registers and my eyes search for your age, complete disquiet washes over me when I read you are only seven.
Ann Intern Med. 2017;166(11):854. doi:10.7326/M16-2139
Ann Intern Med. 2017;166(11):855. doi:10.7326/L17-0211
Ann Intern Med. 2017;166(11):855. doi:10.7326/L17-0212
Ann Intern Med. 2017;166(11):856. doi:10.7326/L17-0147
Ann Intern Med. 2017;166(11):856. doi:10.7326/L17-0148
Ann Intern Med. 2017;166(11):856. doi:10.7326/M17-0898
Shahnaz Sultan, MD, MHSc; Ashish Malhotra, MD
Ann Intern Med. 2017;166(11):ITC81-ITC96. doi:10.7326/AITC201706060
Darren B. Taichman, MD, PhD
Ann Intern Med. 2017;166(11):ED11. doi:10.7326/AFED201706060
Vun Peng Chang, MBBS; Ben Mitchell, BA (Hons)
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2017;166(11):W57-W63. doi:10.7326/G16-0028
Ann Intern Med. 2017;166(11):I-24. doi:10.7326/P17-9038
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