Alex Tsodikov, PhD; Roman Gulati, MS; Eveline A.M. Heijnsdijk, PhD; Paul F. Pinsky, PhD; Sue M. Moss, PhD; Sheng Qiu, MS; Tiago M. de Carvalho, MS; Jonas Hugosson, MD; Christine D. Berg, MD; Anssi Auvinen, MD; Gerald L. Andriole, MD; Monique J. Roobol, PhD; E. David Crawford, MD; Vera Nelen, MD; Maciej Kwiatkowski, MD; Marco Zappa, PhD; Marcos Luján, MD; Arnauld Villers, MD; Eric J. Feuer, PhD; Harry J. de Koning, MD; Angela B. Mariotto, PhD; Ruth Etzioni, PhD
In 2012, the U.S. Preventive Services Task Force recommended against routine use of prostate-specific antigen screening, relying heavily on results from the ERSPC (European Randomized Study of Screening for Prostate Cancer) and the PLCO (Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial), which had conflicting results. In this study, the authors formally tested whether mortality differed between the ERSPC and PLCO after accounting for certain differences.
Ann Intern Med. 2017;167(7):449-455. doi:10.7326/M16-2586
Jarrod E. Dalton, PhD; Adam T. Perzynski, PhD; David A. Zidar, MD; Michael B. Rothberg, MD, MPH; Claudia J. Coulton, PhD; Alex T. Milinovich, BA; Douglas Einstadter, MD, MPH; James K. Karichu, PhD; Neal V. Dawson, MD
Using an observational cohort analysis, the authors studied the predictive accuracy of the Pooled Cohort Equations Risk Model of the American College of Cardiology and American Heart Association in relation to information on the socioeconomic characteristics of a patient's neighborhood of residence.
Ann Intern Med. 2017;167(7):456-464. doi:10.7326/M16-2543
Keith M. Diaz, PhD; Virginia J. Howard, PhD; Brent Hutto, MSPH; Natalie Colabianchi, PhD; John E. Vena, PhD; Monika M. Safford, MD; Steven N. Blair, PED; Steven P. Hooker, PhD
Although total sedentary time has been associated with increased mortality, most studies have relied on participant recall to report activity. Whether longer or shorter bouts of inactivity are associated with different outcomes is not known. This large cohort study objectively measured physical activity to assess total as well as shorter and longer bouts of sedentary time.
Ann Intern Med. 2017;167(7):465-475. doi:10.7326/M17-0212
Andreas Goebel, MD, PhD; Jatinder Bisla, BSc; Roy Carganillo, RN; Bernhard Frank, MD; Rima Gupta, BSc (Pharm); Joanna Kelly, MSc; Candy McCabe, PhD; Caroline Murphy, MSc; Nick Padfield, MD; Ceri Phillips, PhD; Mark Sanders, MD; Mick Serpell, MD; Nick Shenker, MD, PhD; Karim Shoukrey, MD; Lynne Wyatt, BSc; Gareth Ambler, PhD
Complex regional pain syndrome (CRPS) is a rare posttraumatic pain condition with few effective treatment options. This randomized placebo-controlled trial evaluated the effectiveness of low-dose intravenous immunoglobulin in reducing pain during a 6-week period in adults with long-standing CRPS.
Ann Intern Med. 2017;167(7):476-483. doi:10.7326/M17-0509
Gerald W. Smetana, MD; Marc Schermerhorn, MD; Kenneth J. Mukamal, MD
In this grand rounds discussion, a vascular surgeon and a primary care physician share perspectives on whether a 74-year-old man with risk factors for cardiovascular disease should be screened for carotid artery stenosis.
Ann Intern Med. 2017;167(7):484-492. doi:10.7326/M17-1345
James J. Chamberlain, MD; Rita Rastogi Kalyani, MD, MHS; Sandra Leal, PharmD, MPH; Andrew S. Rhinehart, MD; Jay H. Shubrook, DO; Neil Skolnik, MD; William H. Herman, MD, MPH
This synopsis focuses on the 2017 American Diabetes Association recommendations about monitoring and pharmacologic approaches to glycemic management for type 1 diabetes.
Ann Intern Med. 2017;167(7):493-498. doi:10.7326/M17-1259
David A. Asch, MD, MBA; Kevin G. Volpp, MD, PhD
Investment in discovering transformative health care interventions favors future generations that might realize its large but distant benefits, but it shortchanges current generations who could immediately benefit from the “halfway technologies” that get us pretty far but not to the moon.
Ann Intern Med. 2017;167(7):505-506. doi:10.7326/M17-1449
Arabella L. Simpkin, MD, MMSc; Jatin M. Vyas, MD, PhD; Katrina A. Armstrong, MD, MSCE
In this essay, the authors describe several initiatives at their institution to foster the development of diagnostic reasoning skills among internal medicine residents.
Ann Intern Med. 2017;167(7):507-508. doi:10.7326/M17-0163
Pamela S. Belperio, PharmD; Maggie Chartier, PsyD, MPH; David B. Ross, MD, PhD, MBI; Poonam Alaigh, MD; David Shulkin, MD
In this article, the authors discuss important actions Veterans Affairs (VA) has taken to reduce the burden of hepatitis C virus infection and the ways in which the VA care model can be implemented in non-VA settings.
Ann Intern Med. 2017;167(7):499-504. doi:10.7326/M17-1073
Andrew J. Vickers, PhD
The editorialist discusses Tsodikov and colleagues' findings and advocates for a shift in focus, from whether screening with prostate-specific antigen testing provides benefit to how to implement screening so that the benefits outweigh the harms.
Ann Intern Med. 2017;167(7):509-510. doi:10.7326/M17-2012
Sandro Galea, MD, DrPH; Katherine M. Keyes, PhD
The editorialists discuss Dalton and colleagues' article and see it as a sobering reminder of the limitations of predictive models that fail to consider base prevalence and co-occurring factors.
Ann Intern Med. 2017;167(7):511-512. doi:10.7326/M17-1733
David A. Alter, MD, PhD
Diaz and colleagues' study tracked physical activity in adults aged 45 years or older and showed a strong relationship between daily volume of sedentary behavior and all-cause mortality. The editorialist discusses the findings and strategies that are needed to reduce daily sedentary volume and uninterrupted sedentary bout lengths.
Ann Intern Med. 2017;167(7):513-514. doi:10.7326/M17-2181
Frank Birklein, MD; Claudia Sommer, MD
Goebel and colleagues report a randomized trial of intravenous immunoglobulin to treat chronic complex regional pain syndrome. The editorialists discuss the pathophysiology of this syndrome and explain why they are not ready to abandon hope for the effectiveness of immunomodulatory therapy, despite the disappointing results observed in this trial.
Ann Intern Med. 2017;167(7):515-516. doi:10.7326/M17-1943
Elizabeth Ricanati, MD
The rape kit just sat there on the cold metal table next to the cot, daring me to open it, to begin the examination.
Ann Intern Med. 2017;167(7):517-518. doi:10.7326/M17-0135
Ann Intern Med. 2017;167(7):519-521. doi:10.7326/M17-0695
Ann Intern Med. 2017;167(7):521. doi:10.7326/L17-0282
Ann Intern Med. 2017;167(7):521-522. doi:10.7326/L17-0283
Ann Intern Med. 2017;167(7):522. doi:10.7326/L17-0268
Ann Intern Med. 2017;167(7):523-524. doi:10.7326/L17-0267
Ann Intern Med. 2017;167(7):523. doi:10.7326/L17-0269
Ann Intern Med. 2017;167(7):524. doi:10.7326/L17-0270
Ann Intern Med. 2017;167(7):524-525. doi:10.7326/L17-0314
Ann Intern Med. 2017;167(7):525-526. doi:10.7326/L17-0315
Ann Intern Med. 2017;167(7):526-527. doi:10.7326/L17-0324
Ann Intern Med. 2017;167(7):526. doi:10.7326/L17-0325
Ann Intern Med. 2017;167(7):527. doi:10.7326/L17-0326
Ann Intern Med. 2017;167(7):528. doi:10.7326/L17-0538
Ann Intern Med. 2017;167(7):528. doi:10.7326/L17-0539
Adam E. Mikolajczyk, MD
Ann Intern Med. 2017;167(7):518. doi:10.7326/M17-1267
Kalpana Gupta, MD, MPH; Larissa Grigoryan, MD, PhD; Barbara Trautner, MD, PhD
Ann Intern Med. 2017;167(7):ITC49-ITC64. doi:10.7326/AITC201710030
Darren B. Taichman, MD, PhD
Ann Intern Med. 2017;167(7):ED7. doi:10.7326/AFED201710030
Allison K. Weinstock, BA
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2017;167(7):W41-W46. doi:10.7326/G17-0006
Ann Intern Med. 2017;167(7):I-16. doi:10.7326/P17-9043
Ann Intern Med. 2017;167(7):I-24. doi:10.7326/P17-9045
Ann Intern Med. 2017;167(7):I-26. doi:10.7326/P17-9046
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