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Learning the Respective Roles of Warfarin and Dabigatran to Prevent Stroke in Patients With Nonvalvular Atrial Fibrillation

Rebecca J. Beyth, MD; and C. Seth Landefeld, MD
[+] Article, Author, and Disclosure Information

From North Florida/South Georgia Veterans Health System and University of Florida, Gainesville, FL 32608-1197; and University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA 94118.

Potential Conflicts of Interest: Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M11-2436.

Requests for Single Reprints: C. Seth Landefeld, MD, Division of Geriatrics, University of California, San Francisco, Suite 380, 3333 California Street, San Francisco, CA 94118.

Current Author Addresses: Dr. Beyth: Division of Geriatrics, University of Florida, 1601 Southwest Archer Road, Gainesville, FL 32608-1197.

Dr. Landefeld: Division of Geriatrics, University of California, San Francisco, Suite 380, 3333 California Street, San Francisco, CA 94118.

Ann Intern Med. 2011;155(10):714-715. doi:10.7326/0003-4819-155-10-201111150-00012
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Should dabigatran replace warfarin in patients with nonvalvular atrial fibrillation? In this issue, Oldgren and colleagues address whether outcomes with dabigatran and warfarin differ according to baseline risk for stroke and provide novel data on all-cause mortality, and Schulman and colleagues compared warfarin dosing assessment every 12 weeks versus every 4 weeks. The editorialists discuss these articles and describe how they can help physicians choose whether to use dabigatran or warfarin to reduce the risk for stroke or systemic embolism in patients with nonvalvular atrial fibrillation.

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