Glomerular filtration rate is a measure of kidney function and can be estimated using equations that are based on the measurement of levels of creatinine, a substance in the blood. It is also possible to look for CKD by measuring urinary levels of a substance called albumin. Chronic kidney disease is most common in people with high blood pressure or diabetes, and people with these conditions should talk to their doctors about being periodically tested for CKD. However, CKD can occur in apparently healthy people who do not have high blood pressure or diabetes. For this reason, the USPSTF aimed to determine whether routine screening of healthy adults for CKD would improve patient outcomes.