The average age of patients in the database increased between 2000 and 2010, and the survival of patients with CF has improved. Overall, male patients have better survival than females, as do patients with no symptoms at diagnosis. Patients with certain gene abnormalities seem to have worse survival than others. If no further improvements in survival occur, males born and diagnosed with CF in 2010 would be expected to live an average of about 40 years and females would be expected to live about 37 years. If survival continues to improve at the rate observed between 2000 and 2010, a person born and diagnosed in 2010 would be expected to live more than 50 years.