The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

Genomics: Prediction, Prevention, Priorities, and PunnettGenomics: Prediction, Prevention, Priorities, and Punnett

Michael F. Murray, MD
[+] Article, Author, and Disclosure Information

This article was published at www.annals.org on 26 January 2016.

From Geisinger Health System, Forty Fort, Pennsylvania.

Disclosures: The author has disclosed no conflicts of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M15-2993.

Requests for Single Reprints: Michael F. Murray, MD, Genomic Medicine Institute, Geisinger Health System, 190 Welles Street, Suite 128, Forty Fort, PA 18704; e-mail, mfmurray1@geisinger.edu.

Ann Intern Med. 2016;164(3):197-198. doi:10.7326/M15-2993
Text Size: A A A

In this issue, Christensen and colleagues found that disclosure of unexpected genomic risk information to healthy adults did not have adverse psychological effects. The editorialist discusses the study and argues that prioritization of which genomic results to disclose to healthy patients should be based on the predictive and preventive value of the result and the costs of delivering the information.


genomics ; genome

First Page Preview

View Large
First page PDF preview


Grahic Jump Location

Clinical genomics Punnett square.

This new version of the Punnett square provides a framework for use in setting priorities for returning genomic information to healthy patients. Genomic results in the HH quadrant should be the highest priority in a health care context.

Grahic Jump Location




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $32.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.